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Found 28 clinical trials
Featured trial
Do you suffer from Hemorrhoids?

Do you suffer from Hemorrhoids?

  • 1577 views
  • 25 Mar, 2021
  • 1 location
A Pragmatic Trial of Pharmacotherapy Options Following Unsatisfactory Initial Treatment in OCD (Proceed)

This study includes a sequenced clinical trial in order to assess the efficacy of several switching or augment strategies when initial treatment is ineffective,and to provide strong evidence for clinical practice and international guidelines for Obsessive-Compulsive Disorder treatments.

fluvoxamine
memantine
treatment regimen
psychotherapy
sertraline
  • 5 views
  • 15 Sep, 2022
  • 1 location
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

The purpose of this study is to assess the safety and tolerability of Seltorexant as adjunctive therapy to an antidepressant in adolescents with major depressive disorder (MDD) in the short-term compared with placebo.

  • 1 views
  • 10 Jul, 2022
  • 12 locations
The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children

To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children

  • 0 views
  • 26 Jan, 2021
  • 1 location
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)

data are demonstrating that serotonergic pathways can regulate ANS discharge. Generally, serotonergic pathways are inhibitory but both single and longer term administration of selective serotonin

Accepts healthy volunteers
glycosylated hemoglobin
hypoglycemia
insulin
sugars
  • 221 views
  • 27 Apr, 2022
  • 1 location
A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder

A 12-week, randomized controlled trial (RCT) will be conducted to explore the effect of add-on sulforaphane (SFN) to selective serotonin reuptake inhibitors (SSRIs) for major depressive disorder

Accepts healthy volunteers
  • 0 views
  • 18 Dec, 2021
  • 1 location
Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder

and norepinephrine transporter inhibitory action. So, the investigators expect that adding dextromethorphan to selective serotonin reuptake inhibitors (SSRIs) regimen can improve clinical outcomes in

  • 0 views
  • 23 Mar, 2022
  • 1 location
A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression

structure change of three different mechanisms of antidepressant drugs, selective serotonin reuptake inhibitors (SSRIs, escitalopram), serotonin and norepinephrine reuptake inhibitors (SNRIs, duloxetine

Accepts healthy volunteers
citalopram
dysthymic disorder
bupropion
norepinephrine
  • 8 views
  • 12 Feb, 2022
  • 1 location
Partners in Caring for Anxious Youth

comparative efficacy study remission occurred in about 65% of children and adolescents treated with a combination of a selective serotonin reuptake inhibitors (SSRI) and cognitive behavioral therapy (CBT). In

  • 0 views
  • 10 Sep, 2021
  • 3 locations
Distress Tolerance for Benzodiazepine Discontinuation (DT-BD)

The proposed study is a clinical trial, designed to pilot test a Distress Tolerance-Benzodiazepine Discontinuation (DT-BD) intervention for patients on opioid agonist therapy (OAT) who currently use benzodiazepines versus a Relaxation Therapy (RT) control condition. The DT-BD intervention is an adjunctive psychosocial intervention in people seeking to discontinue (BZD) use.

benzodiazepines
opioid
toxicology screen
  • 0 views
  • 04 Oct, 2022
  • 1 location