Found 19 clinical trials
Do you suffer from Hemorrhoids?
Do you suffer from Hemorrhoids?
- 1577 views
- 25 Mar, 2021
- 1 location
Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)
There are few treatment options available for patients once they have failed standard psychopharmacological therapy for generalized anxiety disorder. Existing brain stimulation methods such as rTMS fail to target deep brain structures associated with anxiety disorders; structures such as the amygdala. In this double-blind sham-controlled clinical trial, the investigators propose …
- 0 views
- 14 Aug, 2023
- 3 locations
Pragmatic Trial of Obsessive-compulsive Disorder (Proceed)
This study includes a sequenced clinical trial in order to assess the efficacy of several switching or augment strategies when initial treatment is ineffective，and to provide strong evidence for clinical practice and international guidelines for Obsessive-Compulsive Disorder treatments.
- 5 views
- 07 Oct, 2022
- 1 location
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy
The purpose of this study is to assess the safety and tolerability of Seltorexant as adjunctive therapy to an antidepressant in adolescents with major depressive disorder (MDD) in the short-term compared with placebo.
- 8 views
- 18 Sep, 2023
- 21 locations
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
data are demonstrating that serotonergic pathways can regulate ANS discharge. Generally, serotonergic pathways are inhibitory but both single and longer term administration of selective serotonin
- 221 views
- 27 Apr, 2022
- 1 location
Partners in Caring for Anxious Youth
comparative efficacy study remission occurred in about 65% of children and adolescents treated with a combination of a selective serotonin reuptake inhibitors (SSRI) and cognitive behavioral therapy (CBT). In
- 0 views
- 10 Sep, 2021
- 3 locations
Distress Tolerance for Benzodiazepine Discontinuation (DT-BD)
The proposed study is a clinical trial, designed to pilot test a Distress Tolerance-Benzodiazepine Discontinuation (DT-BD) intervention for patients on opioid agonist therapy (OAT) who currently use benzodiazepines versus a Relaxation Therapy (RT) control condition. The DT-BD intervention is an adjunctive psychosocial intervention in people seeking to discontinue (BZD) use.
- 0 views
- 04 Oct, 2022
- 1 location
Citalopram as a Posterior Cortical Protective Therapy in Parkinson Disease
This Parkinson disease (PD) trial will test whether 26 months of citalopram, compared to placebo, can alter the build-up of toxic amyloid-beta plaques in the visuospatial cortex of the brain linked to visuospatial cognitive impairment in PD.
- 0 views
- 19 Apr, 2022
- 1 location
Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder
Acupoints are the stimulus points and reactive points for acupuncture to treat diseases. Therefore, this study is designed to detect the pain threshold and temperature of biological specificities of acupoints in healthy control (HC) participants and major depressive disorder (MDD) participants by using pressure pain threshold gauge (PTG) and infrared …
- 0 views
- 07 Oct, 2022
- 1 location
The Role of Serotonin in Compulsive Behavior in Humans: Underlying Brain Mechanisms
The aim of this project is to investigate: The status of the central serotonin (5-hydroxytryptamine, 5-HT) system in compulsive behaviour and how it is affected by sub-chronic escitalopram administration The mechanisms underlying how sub-chronic administration of escitalopram affects the central 5-HT system How changes in cognitive performance, including the balance …
- 0 views
- 24 Jan, 2021
- 1 location
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