Found 27 clinical trials
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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For all genders
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Currently Recruiting
Do you suffer from Hemorrhoids?
Do you suffer from Hemorrhoids?
- 1312 views
- 25 Mar, 2021
- 1 location
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Phase 4 trial
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Accepting pediatric ages
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Psychiatry/Psychology
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Currently Recruiting
Treatment Youth With Obsessive-Compulsive Disorder
Although research suggests that patients with obsessive-compulsive disorder (OCD) exhibit specific deficits in their high cognitive processes, it is still unknown how these deficits relate to the clinical symptoms of the disorder, and to the response to treatment. There are two aims for the proposed research. The first is to …
- 134 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Psychiatry/Psychology
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Currently Recruiting
Clinical Study on Options of Medication Regimen in Treatment of Refractory Obsessive-Compulsive Disorder Patients
This study includes a two-step clinical trial in order to assess the efficacy of several switching or augment strategies when initial treatment is ineffectiveand to provide strong evidence for clinical practice and international guidelines for Obsessive-Compulsive Disorder treatments.
- 0 views
- 27 Jan, 2021
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor in Participants With Treatment Resistant Major Depressive Disorder
The primary purpose of this study is to evaluate the efficacy of flexibly dosed esketamine nasal spray compared with quetiapine extended-release (XR), both in combination with a continuing selective serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor (SSRI/SNRI), in achieving remission in participants who have treatment-resistant major depressive disorder (MDD) with a current …
- 0 views
- 05 May, 2021
- 213 locations
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children
To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children
- 0 views
- 26 Jan, 2021
- 1 location
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression
structure change of three different mechanisms of antidepressant drugs, selective serotonin reuptake inhibitors (SSRIs, escitalopram), serotonin and norepinephrine reuptake inhibitors (SNRIs, duloxetine
- 8 views
- 23 Jan, 2021
- 1 location
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Effect of Serotonergic Stimulation on the Gut-brain Axis
Selective serotonin reuptake inhibitors increase the level of serotonin. This study will use functional magnetic resonance imaging to examine how subjects with, and without, irritable bowel
- 20 views
- 07 Mar, 2021
- 4 locations
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Endocrinology
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Currently Recruiting
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
data are demonstrating that serotonergic pathways can regulate ANS discharge. Generally, serotonergic pathways are inhibitory but both single and longer term administration of selective serotonin
- 145 views
- 11 Apr, 2021
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Partners in Caring for Anxious Youth
comparative efficacy study remission occurred in about 65% of children and adolescents treated with a combination of a selective serotonin reuptake inhibitors (SSRI) and cognitive behavioral therapy (CBT). In
- 0 views
- 19 Feb, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Psychiatry/Psychology
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Currently Recruiting
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations. Half of participants will receive Ketamine and Milnacipran in combination, while the other half will receive a Placebo and Milnacipran in combination.
- 14 views
- 27 Jan, 2021
- 9 locations