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Found 1205 clinical trials
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Studying the Effects of Natural Visual Scene Changes on Typical Adult Visual Perception

The natural visual environment is complex and rich with different stimuli and features. The visual system must constantly extract behaviorally relevant visual information from an abundance of irrelevant information in the visual scene. To complicate matters further, the visual feature or stimulus that is most relevant at any given moment …

  • 0 views
  • 29 Aug, 2021
  • 1 location
None
Glucose Brain and Microbiota

The accumulation of iron is known to affect the functions of the liver, adipose tissue and muscle. The brain is a well-known place of iron deposition, which is associated with cognitive parameters of subjects with obesity. The hypothesis is that certain parameters related to glucose metabolism (glycemic variability, the circulating …

hemoglobin a1c
glycosylated hemoglobin
bariatric surgery
  • 0 views
  • 24 Jul, 2021
  • 1 location
None
Results of the Aortic Valve Reconstruction in Children

Aortic valve disease counts up to 5% of cases of congenital heart disease being one of the most common congenital malformations of the cardiovascular system. This disease requires replacement of the damaged valve which in itself is not a trivial task to complete in children as there is still no …

computed tomography
heart failure
ejection fraction
transesophageal echocardiography
heparin
  • 0 views
  • 16 Mar, 2021
  • 1 location
None
ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators

The investigators propose a test of causality by examining a cohort of patients undergoing deep brain stimulation (DBS) within the ventral striatum. The investigators will examine behavior on and off stimulation across a range of tasks that index different forms of impulsivity. Patients will be studied in both the ON …

deep brain stimulation
aversion
brain stimulation
  • 64 views
  • 11 Apr, 2021
  • 2 locations
None
Genomic and Phenotypic Determinants of Resistance to Immunotherapies in Multiple Myeloma

A total of 40 Multiple Myeloma (MM) patients at clinical relapse who progressed during Proteasome Inhibitors (PIs) or Immunomodulating Drugs (IMiDs)-based therapies and who are assigned to antiCD38-based salvage treatments, will be enrolled. We will collect bone marrow (BM) and peripheral blood (PB) samples from patients at specific timepoints: baseline …

  • 0 views
  • 07 May, 2021
  • 1 location
None
CGRP Inhibition Autonomic Function and Migraine

The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e. whether they are between or during attacks) and whether the CGRP monoclonal antibody (mAb) …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Blood Management During ECMO for Cardiac Support

Extracorporeal membrane oxygenation (ECMO) is a lifesaving procedure used to treat severe forms of heart and/or lung failure. It works by the principal of replacing the function of these organs by taking blood from the patient, provide it with oxygen outside the body and return it to the patient in …

heart failure
mechanical circulatory support
membrane oxygenation
heparin
coagulopathy
  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Virtual Reality for Children's Blood Sampling

Virtual Reality (VR) is technology that simulates an immersive 3 dimensional environment for the user and is often used for immersive gaming experiences. The investigators will use VR in children who undergo painful procedures such as blood sampling and cannulation to investigate if VR reduces pain. The study will be …

  • 0 views
  • 04 Sep, 2021
  • 2 locations
None
Comprehensive Process Model of AA-related Behavior Change

Alcoholics Anonymous (AA) is one of the most popular resources for dealing with alcohol-related problems, and 12-step therapy (TS), based upon AA doctrine and practice, is one of the prevailing alcohol treatment approaches in the United States. Two large multisite trials, one high in internal validity and the second high …

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Screening of Susceptibility Genes for APAP Induced Drug Induced LIver Injury in ChiNese Population: a Case-control Study

Acetaminophen (APAP) is the most commonly used NSAIDS in clinic, and it is also a common cause of drug-induced liver injury (DILI). In 2012, the proportion of DILI caused by APAP in the United States was 51%, while in Asia, it was only 7.10%. Previously, a small cohort study in …

  • 0 views
  • 25 Jul, 2021
  • 1 location