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Found 1206 clinical trials
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Apoptosis Markers in Aggressive Periodontitis

The aim of the present trial is to assess the gingival crevicular fluid level of caspase-3 and apoptosis inducing factor (AIF) in Generalized versus Molar-incisor grade C periodontitis. The present study will be carried out on patients selected from those attending on the outpatient clinics of Department of Oral Medicine, …

  • 0 views
  • 19 Aug, 2021
  • 1 location
None
Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases

In this observational study, data from patients treated with the antibiotic ceftobiprole in the past will be collected. The sponsor of the study is Correvio International Srl, based in Switzerland. Correvio has committed to the health authorities to obtain further information on possible side effects especially in patients suffering from …

liver disease
immunosuppression
liver failure
nephropathy
cirrhosis
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Imaging Biomarkers in Parkinson s Disease

Background Parkinson s disease (PD) causes slow movement, stiffness, and tremor. It results from the loss of a brain chemical called dopamine. PD gets worse over time, but researchers do not fully understand why the brain cells that produce dopamine stop working or die in people with PD. This study …

Accepts healthy volunteers
tremor
dopamine
cognitive decline
  • 68 views
  • 05 Dec, 2021
  • 1 location
None
The Effects of Posture on Cerebral Blood Flow Velocity During the Acute Phase of Stroke

After stroke, blood vessels in the brain can become damaged, and the brain's ability to control blood flow can be impaired. The brain therefore may be less able to maintain a healthy level of blood flow during challenges such as changes in posture. Studies have shown that sitting upright early …

  • 0 views
  • 11 Nov, 2021
  • 1 location
None
Surgeon Ergonomics in Robotic-assisted Laparoscopic Vs Standard Laparoscopic Surgery

Musculoskeletal injuries amongst surgeons are prevalent. This project will determine whether Robotic-assisted Laparoscopic surgery (RALS) offers superior benefits to surgeon's musculoskeletal health than standard laparoscopic surgery (LS), by identifying the comparative changes in muscle fatigue during RALS Vs LS surgical procedures, and additionally identify any cognitive effects of this. The …

Accepts healthy volunteers
  • 0 views
  • 09 Nov, 2021
  • 2 locations
None
Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia

CDH is associated with lung hypoplasia, pulmonary hypertension, and left ventricular hypoplasia. Use of new STE techniques (heart ultrasound) showed that CDH newborns have decreased LV size and function, potentially explaining the non-response to iNO, and that these cardiac findings were associated with poor outcomes. Our hypothesis: CDH newborns persist …

hypertension
pulmonary hypoplasia
diaphragmatic hernia
  • 0 views
  • 22 Jun, 2021
  • 1 location
None
Sepsis Associated Encephalopathy (SAE) Biomarkers

Sepsis associated encephalopathy (SAE) is a poorly understood acute cerebral dysfunction that frequently appears in the setting of sepsis induced systemic inflammation. In fact, altered mentation is recognized as an independent predictor of death and poor outcomes in patients with sepsis. SAE may be manifested by a number of symptoms …

antibiotic therapy
blood culture
inflammatory response
systemic inflammatory response syndrome
carbon dioxide
  • 18 views
  • 09 Jul, 2021
  • 1 location
None
Raman Analysis of Saliva as Biomarker of COPD

Chronic Obstructive Pulmonary Disease (COPD) is a debilitating and chronic lung syndrome that causes accelerated lung function decline and death in 20% of cases. The worsening of symptoms, as well as the patient's condition, strictly depends on the identified COPD phenotype, severity stages, exacerbation events, selected drugs, rehabilitation cures and …

  • 2 views
  • 27 Jan, 2021
  • 1 location
None
Safer Online Lives: Use of the Internet & Social Media by People With Intellectual Disabilities

The objective of this study is to explore the benefits of internet use for people with intellectual disabilities (ID), the risks they might come up against while online, the barriers people with ID might come across due to the 'digital divide', and the opportunities offered by being online. The views …

  • 0 views
  • 28 Jun, 2021
  • 1 location
None
Transoral Incisionless Fundoplication in Post-POEM GERD

POEM (per oral endoscopic myotomy) is effective for the treatment of swallowing disorders but can induce acid reflux. If acid reflux remains untreated in this situation, it can lead to significant problems. Thus, minimizing abnormal acid exposure after POEM is very important. Typically, this is done with acid suppression medications …

  • 0 views
  • 10 May, 2021
  • 1 location