Found 1185 clinical trials
Raman Analysis of Saliva as Biomarker of COPD
Chronic Obstructive Pulmonary Disease (COPD) is a debilitating and chronic lung syndrome that causes accelerated lung function decline and death in 20% of cases. The worsening of symptoms, as well as the patient's condition, strictly depends on the identified COPD phenotype, severity stages, exacerbation events, selected drugs, rehabilitation cures and …
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- 27 Jan, 2021
- 1 location
Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia
CDH is associated with lung hypoplasia, pulmonary hypertension, and left ventricular hypoplasia. Use of new STE techniques (heart ultrasound) showed that CDH newborns have decreased LV size and function, potentially explaining the non-response to iNO, and that these cardiac findings were associated with poor outcomes. Our hypothesis: CDH newborns persist …
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- 22 Jun, 2021
- 1 location
Cardiac Markers in Depressed Patients With Coronary Heart Disease
Depression doubles the risk of death in patients with coronary heart disease (CHD), but so far, there is insufficient evidence that we can reduce the risk of death by treating depression. This study will investigate the cardiac risk markers that are associated with depression symptoms that remain despite treatment, and …
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- 27 Jan, 2021
- 1 location
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation
The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) (www.elipto.ca) is to improve the perioperative care of liver transplant recipients. One of this program's purposes is to better define the effects of intraoperative hemodynamic management on postoperative outcomes in adult liver transplant recipients. …
- 9 views
- 24 Sep, 2021
- 1 location
Needs Assessment for Bereaved Families
The present study will focus on several objectives in the framework of the family perspective and systemic understanding of the mourning process: 1. Identification of the psychological, social and practical needs of families that have lost a child to terrorism. 2. Deepening and extending the knowledge of how families cope …
- 26 views
- 07 Nov, 2020
- 1 location
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer with the use of an Automated External Defibrillator (AED). This latter realizes a cardiac rhythm analysis …
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- 15 Oct, 2021
- 1 location
Epigenetics and Protective Factors in the Preterm Infant
Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in epigenetic regulation (DNA methylation). Recent studies document that these epigenetic changes are associated with behavioral modifications, such …
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- 07 Sep, 2021
- 1 location
Perioperative Evaluation of Cerebellar Tumors
This is a prospective, cohort study to evaluate the impact of cerebellar functional topography on perioperative outcomes related to cognition and motor ataxia in patients with cerebellar tumors.
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- 17 Mar, 2021
- 1 location
Fluid Intake After Hemodialysis
Interdialytic weight gain determines how much fluid (ultrafiltration) has to be removed during each hemodialysis session. High ultrafiltration volumes stress the organism and lead to a higher risk of death. Thirst is the main driving factor of interdialytic weight gain, and thirst is mainly driven by salt intake, molecules that …
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- 08 Apr, 2021
- 2 locations
Famine From Feast: Linking Vitamin C Red Blood Cell Fragility and Diabetes
Diabetes type two is a debilitating disease that leads to chronic morbidity such as accelerated microvascular disease. Accelerated microvascular disease may produce blindness, end stage renal disease, myocardial infarction, stroke, and limb ischemia. Strategies to prevent or delay microvascular disease have the potential to improve the lives of millions and …
- 9 views
- 22 May, 2021
- 1 location