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Found 1205 clinical trials
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Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease

The investigators propose a study to assess cognitive and developmental outcomes of patients with CLN2 that are untreated and receiving cerliponase alfa. This study aims to validate standardized assessment measures to establish a standard of care. The secondary aim is to compare cognitive and developmental outcomes of patients with CLN2 …

  • 0 views
  • 13 Aug, 2021
  • 1 location
None
Benefit Usage and Comfort of Treatment of OSA With a Mandibular Advancement Device: Narval Registry

During sleep, the muscle tonus in the oropharyngeal space is lost, the tongue might fall back andthe volume of the pharynx decreases. Air cannot pass through as it would in the awake state and thus airflow limitations occur. The person asleep might compensate the flow limitation by breathing faster, which …

collapse
mandibular advancement
oropharyngeal
snoring
  • 12 views
  • 25 Jan, 2021
  • 1 location
None
Cannabis Use in Cancer Patients

The goal of this study is to determine the feasibility of a human observational study of orally administered cannabis use among cancer patients.

solid tumor
cancer
  • 1 views
  • 13 Oct, 2021
  • 2 locations
None
Relevant Factors on Sprint Performance in Adolescent Sprinters

Purpose: To explore the sports performance of the adolescent sprinters, including analyzing the correlations between the results and central nerve sensory, and also between motor control and various muscle mechanical characteristic and sport-related fitness factor.

Accepts healthy volunteers
  • 0 views
  • 25 Nov, 2021
  • 1 location
None
Is Cefazolin Ceftazidime and Ciprofloxacin Dosing Optimal in Hemodialysis Patients?

This study aims to optimize the dosing of cefazolin, ceftazidime, and ciprofloxacin for patients on high-flux hemodialysis. For each antibiotic 20 participants will be enrolled and three blood samples will be collected from each participant. Antibiotic levels will be measured in each blood sample. This data will be used to …

  • 0 views
  • 07 May, 2021
  • 2 locations
None
Adaptive Radiotherapy for High-risk Prostate Cancer Using Multiparametric MRI

This small study will investigate the feasibility of using multi-parametric MRI to introduce and support adaptive radiotherapy treatments for high-risk prostate cancer.

multiparametric magnetic resonance imaging
androgen suppression
antiandrogen therapy
external beam radiotherapy
androgens
  • 1 views
  • 27 Jan, 2021
  • 1 location
None
Natural History Study of ATP1A3-related Disease

An observational study aiming to study the natural history of a UK-wide patient cohort with ATP1A3-related disease.

  • 0 views
  • 18 Feb, 2021
  • 1 location
None
Study on Patients With Rasmussen Encephalitis Treated With Adalimumab: Efficacy and Tolerance in the Short and Long Term

Since the initial study of cases reported between 2009 and 2015, adalimumab has become in France the immunomodulatory reference treatment used after failure of corticosteroids and immunoglobulins before a possible recourse to the hemispherotomy. This observational study is intended to document the long-term efficacy and safety of Adalimumab therapy in …

  • 0 views
  • 29 Aug, 2021
  • 1 location
None
SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)

Overall mortality of COVID-19 is variable and has been reported to be between less than 1% and 7%. Many authors around the world also reported data on hospitalization rate, need for intensive care unit (ICU) care and need for mechanical ventilation in SARS-CoV-2 infected patients. To provide anesthetic and surgical …

fatigue
fever
SARS
myalgia
covid-19
  • 2 views
  • 29 Sep, 2021
  • 1 location
None
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation

The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) (www.elipto.ca) is to improve the perioperative care of liver transplant recipients. One of this program's purposes is to better define the effects of intraoperative hemodynamic management on postoperative outcomes in adult liver transplant recipients. …

liver disease
cirrhosis
liver transplant
  • 9 views
  • 25 Nov, 2021
  • 1 location