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Found 1142 clinical trials
Sepsis Associated Encephalopathy (SAE) Biomarkers

Sepsis associated encephalopathy (SAE) is a poorly understood acute cerebral dysfunction that frequently appears in the setting of sepsis induced systemic inflammation. In fact, altered mentation is recognized as an independent predictor of death and poor outcomes in patients with sepsis. SAE may be manifested by a number of symptoms …

blood culture
carbon dioxide
altered mental status
  • 09 Jul, 2021
  • 1 location
Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia

CDH is associated with lung hypoplasia, pulmonary hypertension, and left ventricular hypoplasia. Use of new STE techniques (heart ultrasound) showed that CDH newborns have decreased LV size and function, potentially explaining the non-response to iNO, and that these cardiac findings were associated with poor outcomes. Our hypothesis: CDH newborns persist …

diaphragmatic hernia
pulmonary hypoplasia
  • 22 Jun, 2021
  • 1 location
Raman Analysis of Saliva as Biomarker of COPD

Chronic Obstructive Pulmonary Disease (COPD) is a debilitating and chronic lung syndrome that causes accelerated lung function decline and death in 20% of cases. The worsening of symptoms, as well as the patient's condition, strictly depends on the identified COPD phenotype, severity stages, exacerbation events, selected drugs, rehabilitation cures and …

  • 27 Jan, 2021
  • 1 location
Needs Assessment for Bereaved Families

The present study will focus on several objectives in the framework of the family perspective and systemic understanding of the mourning process: 1. Identification of the psychological, social and practical needs of families that have lost a child to terrorism. 2. Deepening and extending the knowledge of how families cope …

  • 07 Nov, 2020
  • 1 location
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation

The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) ( is to improve the perioperative care of liver transplant recipients. One of this program's purposes is to better define the effects of intraoperative hemodynamic management on postoperative outcomes in adult liver transplant recipients. …

liver disease
liver transplant
  • 19 Sep, 2021
  • 1 location
Longitudinal Follow-up Study About Complex Regional Pain Syndrome (CRPS) Patients

Complex regional pain syndrome (CRPS) is a post-traumatic chronic pain condition characterized by pain and other symptoms typically affecting a distal limb. Relatively little is known about the prognosis of the course of CRPS .Currently there is no specific test to diagnose CRPS. The primary objective of the study is …

  • 29 Jan, 2021
  • 1 location
Fluid Intake After Hemodialysis

Interdialytic weight gain determines how much fluid (ultrafiltration) has to be removed during each hemodialysis session. High ultrafiltration volumes stress the organism and lead to a higher risk of death. Thirst is the main driving factor of interdialytic weight gain, and thirst is mainly driven by salt intake, molecules that …

  • 08 Apr, 2021
  • 2 locations
Perioperative Evaluation of Cerebellar Tumors

This is a prospective, cohort study to evaluate the impact of cerebellar functional topography on perioperative outcomes related to cognition and motor ataxia in patients with cerebellar tumors.

  • 17 Mar, 2021
  • 1 location
Epigenetics and Protective Factors in the Preterm Infant

Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in epigenetic regulation (DNA methylation). Recent studies document that these epigenetic changes are associated with behavioral modifications, such …

  • 07 Sep, 2021
  • 1 location
The Pathogenesis of Superior Limbic Keratoconjunctivitis

Superior limbic keratoconjunctivitis (SLK) was first described in detail as a clinical entity by Frederick Theodore in 1963. The clinical picture of SLK is well documented, but the etiology is still unknown. This project will be conducted into through two parts: one is to investigate the presentation of chemokine receptors …

  • 07 Nov, 2020
  • 1 location