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Found 1172 clinical trials
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Analysis of Intestinal Microflora Combined With DNA Methylation in Stool to Detect Colorectal Cancer

Introduction: Colorectal cancer (CRC) has the third highest incidence rate and the fourth mortality rate in the world. Traditional colonoscopy as an invasive examination method cannot be widely used in screening for colorectal neoplasia. The fecal immunochemical test has some limitations in sensitivity. Also, race and regional differences may affect …

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
International Rapid-onset Obesity With Hypothalamic Dysfunction Hypoventilation & Autonomic Dysregulation (ROHHAD) Registry

The Center for Autonomic Medicine in Pediatrics (CAMP) has collaborated with doctors from around the world to build the first International ROHHAD (Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation and Autonomic Dysregulation) REDCap (Research Electronic Data Capture) Registry. This registry is an international collaboration with ROHHAD patients and their physicians recruited …

  • 29 views
  • 05 Jul, 2021
  • 1 location
None
Prospective Tissue Collection Research Protocol

This study aims to collect matched donor tissue and blood to enable the development of a manufacturing process for potential immunotherapies.

lung cancer
cancer
aptt
breast cancer
neutrophil count
  • 72 views
  • 02 Sep, 2021
  • 8 locations
None
A Post-market Observational ORIGIN vs. VANGUARD PS Clinical Study

The study objective is to assess patient satisfaction after the surgery with a custom-made CE marked implant (ORIGIN) versus off-the-shelf (VANGUARD PS) device, and to document the clinical and device performance outcomes of the ORIGIN System used in routine hospital practice in a large patient cohort treatment of total knee …

  • 0 views
  • 16 Aug, 2021
  • 1 location
None
Frequent Cuff Inflations May Disrupt the Accuracy of 24-hour Ambulatory Blood Pressure Monitoring

24-hour ambulatory blood pressure monitoring (ABPM) is superior to office blood pressure (BP) for assessing cardiovascular risk. On the other hand, repeated cuff inflations during ABPM can cause discomfort and reduced quality of sleep. A high frequency of measurement during ABPM might result in erroneously high BP measurement, incorrect hypertension …

  • 0 views
  • 11 Mar, 2021
  • 1 location
None
Study on Patients With Rasmussen Encephalitis Treated With Adalimumab: Efficacy and Tolerance in the Short and Long Term

Since the initial study of cases reported between 2009 and 2015, adalimumab has become in France the immunomodulatory reference treatment used after failure of corticosteroids and immunoglobulins before a possible recourse to the hemispherotomy. This observational study is intended to document the long-term efficacy and safety of Adalimumab therapy in …

  • 0 views
  • 29 Aug, 2021
  • 1 location
None
Cannabis Use in Cancer Patients

The goal of this study is to determine the feasibility of a human observational study of orally administered cannabis use among cancer patients.

solid tumor
cancer
  • 1 views
  • 13 Oct, 2021
  • 2 locations
None
Benefit Usage and Comfort of Treatment of OSA With a Mandibular Advancement Device: Narval Registry

During sleep, the muscle tonus in the oropharyngeal space is lost, the tongue might fall back andthe volume of the pharynx decreases. Air cannot pass through as it would in the awake state and thus airflow limitations occur. The person asleep might compensate the flow limitation by breathing faster, which …

snoring
oropharyngeal
mandibular advancement
collapse
  • 12 views
  • 25 Jan, 2021
  • 1 location
None
Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease

The investigators propose a study to assess cognitive and developmental outcomes of patients with CLN2 that are untreated and receiving cerliponase alfa. This study aims to validate standardized assessment measures to establish a standard of care. The secondary aim is to compare cognitive and developmental outcomes of patients with CLN2 …

  • 0 views
  • 13 Aug, 2021
  • 1 location
None
Adaptive Radiotherapy for High-risk Prostate Cancer Using Multiparametric MRI

This small study will investigate the feasibility of using multi-parametric MRI to introduce and support adaptive radiotherapy treatments for high-risk prostate cancer.

antiandrogen therapy
androgens
external beam radiotherapy
multiparametric magnetic resonance imaging
androgen suppression
  • 1 views
  • 27 Jan, 2021
  • 1 location