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Found 1156 clinical trials
PAIN Empathy Assessment in Sleep Deprived Emergency & Acute Care Clinicians (PAIN-EASE)

Cognitive Empathy is relevant in clinical practice and will be assessed based on the accuracy of pain recognition and the pain intensity evaluation in a computerised task using facial expressions. Repeated measures across day and night shifts will provide the basis to understand the impact of shift work on those …

Accepts healthy volunteers
  • 24 Mar, 2022
  • 1 location
Bedside Monitoring to Identify Impaired Cerebral Autoregulation in Women With Postpartum Hypertension

The purpose of this research study is to develop a protocol for NIRS-based bedside monitoring to identify impaired cerebral autoregulation in women admitted to the high-risk obstetrics unit with postpartum hypertension. The investigators will then pilot this protocol in 10 patients with high-risk neurological features, such as headache.

  • 11 Aug, 2022
Ovarian Reserve and Bariatric Surgery

The expansion of the obesity epidemic is accompanied with an increase in bariatric procedures, in particular in women of reproductive age. Severe obesity has negative effects on fertility and on in vitro fertilization (IVF) outcomes, and the weight loss induced by the bariatric surgery (BS) is believed to reverse the …

gastric bypass
sleeve gastrectomy
body mass index
polycystic ovary syndrome
  • 19 Dec, 2021
  • 6 locations
A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women

Pregnant women who are taking lamotrigine will be evaluated monthly during pregnancy including a clinical evaluation and a blood draw for lamotrigine levels at each visit. Based on the Therapeutic Drug Monitoring protocol, participant's lamotrigine dosing will be adjusted as needed based on participant's blood levels compared to the reference …

bipolar disorder
depressive disorder
schizoaffective disorder
  • 21 Feb, 2022
  • 1 location
International Rapid-onset Obesity With Hypothalamic Dysfunction Hypoventilation & Autonomic Dysregulation (ROHHAD) Registry

The Center for Autonomic Medicine in Pediatrics (CAMP) has collaborated with doctors from around the world to build the first International ROHHAD (Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation and Autonomic Dysregulation) REDCap (Research Electronic Data Capture) Registry. This registry is an international collaboration with ROHHAD patients and their physicians recruited …

  • 05 Jul, 2021
  • 1 location
Imaging Biomarkers in Parkinson s Disease

Background Parkinson s disease (PD) causes slow movement, stiffness, and tremor. It results from the loss of a brain chemical called dopamine. PD gets worse over time, but researchers do not fully understand why the brain cells that produce dopamine stop working or die in people with PD. This study …

Accepts healthy volunteers
cognitive decline
  • 22 Jul, 2022
  • 1 location
Cannabis Use in Cancer Patients

The goal of this study is to determine the feasibility of a human observational study of orally administered cannabis use among cancer patients.

solid tumor
  • 24 May, 2022
  • 2 locations
The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies

The investigators aimed to research the incidence of hyperlactatemia in craniotomy cases, the relationship of lactate elevation with tumor type and other factors that may be related, and whether the general anesthesia method applied (inhalation anesthesia or total ıntravenous anesthesia) affects lactate level.

Accepts healthy volunteers
  • 16 Dec, 2021
  • 1 location
Study on Patients With Rasmussen Encephalitis Treated With Adalimumab: Efficacy and Tolerance in the Short and Long Term

Since the initial study of cases reported between 2009 and 2015, adalimumab has become in France the immunomodulatory reference treatment used after failure of corticosteroids and immunoglobulins before a possible recourse to the hemispherotomy. This observational study is intended to document the long-term efficacy and safety of Adalimumab therapy in …

  • 29 Aug, 2021
  • 1 location
Adaptive Radiotherapy for High-risk Prostate Cancer Using Multiparametric MRI (ARPC-MRI)

This small study will investigate the feasibility of using multi-parametric MRI to introduce and support adaptive radiotherapy treatments for high-risk prostate cancer.

antiandrogen therapy
external beam radiotherapy
androgen suppression
multiparametric magnetic resonance imaging
  • 09 Feb, 2022
  • 1 location