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Found 1220 clinical trials
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Is Protein S100B a Predictor of First-to-chronic Seizure Conversion in Adults?

Seizures represent an important clinical problem, accounting for at least 40% of adult onset epilepsy. Predicting seizure recurrence in subjects experiencing a first seizure is difficult due to

seizure
  • 8 views
  • 28 Jan, 2021
  • 3 locations
None
Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients

The purpose of this study is to develop a technique for the intraoperative identification of human functional and epileptiform cortex using intrinsic signal imaging. The investigators propose that the ability to optically monitor neuronal activity in a large area of cortex in "real-time" will be a more sensitive and time-saving …

intractable epilepsy
neurosurgery
seizure
  • 31 views
  • 04 Apr, 2021
  • 1 location
None
The Validity and Reliability of FIT-HaNSA in Breast Cancer Patients

observations and evaluations of the clinicians. Performance tests are important for clinicians to make decisions. With this study, we want to examine the usability of the FIT-HaNSA test in the

  • 0 views
  • 18 Mar, 2021
  • 1 location
None
Clinical Evaluation of the Efficacity of Epilepsy Surgery in Infants and Children

The Pediatric Neurosurgery Service of the Rothschild Foundation (Paris) is the French leader center for surgery of epilepsy in infants and children. Postoperative follow-up of these children is performed during medical and neurosurgical consultations in order to assess the frequency of attacks and to reduce medication. On average, two postoperative …

epilepsy surgery
neurosurgery
  • 13 views
  • 05 Apr, 2021
  • 1 location
None
Brivaracetam: a Prospective and Multicentre Post-marketing Observational Study

Inventory in Epilepsy-10 (QOLIE-10) scale]; e) the proportion of individuals that are seizure free, and f) change in distribution of seizure types (e.g. focal with motor seizures, generalized absence). The

neurological disorder
convulsive seizure
antiepileptics
brivaracetam
generalized seizure
  • 6 views
  • 30 Sep, 2021
  • 1 location
None
RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy

When patients arrive in the waiting room of the MRI department, patients and holders of parental authority will be given the information note explaining the objective of the study and its unfolding. During the consultation, the radiologist will check the inclusion and non-inclusion criteria, and will take the time to …

  • 0 views
  • 21 Jul, 2021
  • 1 location
None
Smartphone Behavior and Epilepsy Management

In this prospective cohort study smartphone behavior surrounding epileptic seizures will be quantified, using a smartphone app, in order to optimize epilepsy evaluation and treatment

  • 0 views
  • 29 Aug, 2021
  • 2 locations
None
Energy Expenditure and Quality of Life in Epilepsy

changes in the frequency and severity of seizures, QoL, energy substrate metabolism, body energy expenditure components, fat mass and fat-free mass in adults with epilepsy. To achieve this objective

atkins diet
ketogenic diet
  • 0 views
  • 01 Nov, 2021
  • 1 location
None
Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Intractable Epilepsy

Deep Brain Stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been proposed in patients with severe intractable epilepsy. When used, the transventricular approach increases the risk of bleeding due the anatomy around the entry point in the thalamus. To avoid such a complication, the investigators used a …

  • 0 views
  • 05 Mar, 2021
  • 1 location
None
Prospective Open-label Evaluation of Cenobamate Adjunctive Treatment of Adults With Refractory Focal Epilepsy

To evaluate the efficacy, safety and tolerability of cenobamate as adjunctive treatment of refractory focal epilepsy

  • 0 views
  • 16 May, 2021
  • 1 location