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Found 1079 clinical trials
Benefit Usage and Comfort of Treatment of OSA With a Mandibular Advancement Device: Narval Registry

During sleep, the muscle tonus in the oropharyngeal space is lost, the tongue might fall back andthe volume of the pharynx decreases. Air cannot pass through as it would in the awake state and thus airflow limitations occur. The person asleep might compensate the flow limitation by breathing faster, which …

mandibular advancement
  • 25 Jan, 2021
  • 1 location
Relevant Factors on Sprint Performance in Adolescent Sprinters

Purpose: To explore the sports performance of the adolescent sprinters, including analyzing the correlations between the results and central nerve sensory, and also between motor control and various muscle mechanical characteristic and sport-related fitness factor.

Accepts healthy volunteers
  • 25 Nov, 2021
  • 1 location
Is Cefazolin Ceftazidime and Ciprofloxacin Dosing Optimal in Hemodialysis Patients?

This study aims to optimize the dosing of cefazolin, ceftazidime, and ciprofloxacin for patients on high-flux hemodialysis. For each antibiotic 20 participants will be enrolled and three blood samples will be collected from each participant. Antibiotic levels will be measured in each blood sample. This data will be used to …

  • 07 May, 2021
  • 2 locations
The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies

The investigators aimed to research the incidence of hyperlactatemia in craniotomy cases, the relationship of lactate elevation with tumor type and other factors that may be related, and whether the general anesthesia method applied (inhalation anesthesia or total ıntravenous anesthesia) affects lactate level.

Accepts healthy volunteers
  • 16 Dec, 2021
  • 1 location
Study on Patients With Rasmussen Encephalitis Treated With Adalimumab: Efficacy and Tolerance in the Short and Long Term

Since the initial study of cases reported between 2009 and 2015, adalimumab has become in France the immunomodulatory reference treatment used after failure of corticosteroids and immunoglobulins before a possible recourse to the hemispherotomy. This observational study is intended to document the long-term efficacy and safety of Adalimumab therapy in …

  • 29 Aug, 2021
  • 1 location
Natural History Study of ATP1A3-related Disease

An observational study aiming to study the natural history of a UK-wide patient cohort with ATP1A3-related disease.

  • 18 Feb, 2021
  • 1 location
SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)

Overall mortality of COVID-19 is variable and has been reported to be between less than 1% and 7%. Many authors around the world also reported data on hospitalization rate, need for intensive care unit (ICU) care and need for mechanical ventilation in SARS-CoV-2 infected patients. To provide anesthetic and surgical …

  • 29 Sep, 2021
  • 1 location
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation

The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) ( is to improve the perioperative care of liver transplant recipients. One of this program's purposes is to better define the effects of intraoperative hemodynamic management on postoperative outcomes in adult liver transplant recipients. …

liver transplant
liver disease
  • 26 Dec, 2021
  • 2 locations
Early Echographic Asystole as a Predictive Factor of Absence of Spontaneous Circulatory Activity Recovery (SCAR) in Prehospital Cardio Respiratory Arrests (CRA)

Assessment of prognostic performances of CCU in CRA Recovery (CRAR) has already been explored but 1) Only in intra-hospital medicine, 2) in very variable timings. ACE Research focuses on the extra-hospital window and predictive value of Early CCU (within 12 minutes of rescucitation initiation) with ambitious endpoints : curable etiologies …

  • 23 Sep, 2021
  • 7 locations
The SMARTChip Stroke Study

Stroke is one of the leading causes of death and disability in the UK and currently costs the country 7bn per year. There is an overwhelming need to accurately and rapidly triage patients to allow best use of finite NHS specialist resources for the treatment of stroke. A simple blood …

  • 28 Jan, 2021
  • 1 location