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Found 20 clinical trials
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PsA Secukinumab XCT Structural Progression Study

through anti IL-17 gives promising clinical improvement. Yet, its effect on radiographic progression remains uncertain. This study aimed to ascertain the effect of secukinumab on structural progression in

anti-rheumatic drugs
arthritis
secukinumab
DMARD
  • 7 views
  • 05 Feb, 2021
  • 1 location
None
Brain Changes in Psoriasis After Secukinumab Treatment

The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate

arthritis
secukinumab
Accepts healthy volunteers
  • 0 views
  • 20 Oct, 2021
  • 1 location
None
Oral Chinese Herbal Medicine Concurrent With Secukinumab for Severe Plaque Psoriasis

The aim of this study is to determine whether oral Chinese herbal medicine in combination secukinumab is effective and safe in the treatment of severe psoriasis.

  • 0 views
  • 11 Mar, 2021
  • 1 location
None
Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis

The purpose of this study is to evaluate efficacy, safety and tolerability of secukinumab in Chinese patients with active nr-axSpA. Treatment difference of secukinumab 150mg vs. placebo in

  • 0 views
  • 08 Dec, 2021
  • 19 locations
None
An Efficacy Study of Secukinumab In Enthesitis of Psoriatic Arthritis Patients

Given the role of IL-17 in the development of entheseal-driven pathology, a therapeutic strategy aimed at blocking IL-17 would be a logical option for the treatment of enthesitis in psoriatic arthritis patients. This study will be the first randomized trial of a biologic therapy in participants with psoriatic arthritis, using …

arthritis
plaque psoriasis
biological drug
enthesitis
secukinumab
  • 0 views
  • 28 Jul, 2021
  • 1 location
None
Study of Efficacy and Safety of Secukinumab in Chinese Subjects With Active PsA Compared to Placebo.

The purpose of this study is to assess the efficacy and safety of secukinumab in Chinese participants with active PsA compared to placebo

rheumatoid factor
plaque psoriasis
dactylitis
leflunomide
psoriasis
  • 0 views
  • 08 Dec, 2021
  • 15 locations
None
Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNF -Inhibitor Treatment

The purpose of this study is to compare the safety and efficacy of secukinumab and ustekinumab in patients with active psoriatic arthritis who showed failure to previous TNF-inhibitor treatment

anti-rheumatic drugs
rheumatoid factor
ustekinumab
tumor necrosis factor
plaque psoriasis
  • 0 views
  • 09 Dec, 2021
  • 27 locations
None
Assessing Patient Confidence in Biologic Medications

), interleukin 12/23 blockers (ustekinumab) and interleukin 17A blockers (secukinumab, ixekizumab). Due to biologic medication's efficacy and safety profiles, they have revolutionized dermatology and the

ustekinumab
tumor necrosis factor
etanercept
tumor necrosis factor alpha
infliximab
  • 67 views
  • 04 Nov, 2021
  • 1 location
None
Scientific Substantiation and Assessment of the Effectiveness of Pathogenetic Methods of Therapy for Congenital Ichthyosis in Children

This is an experimental non-randomized clinical study aimed at expanding the indications for the use of biological drugs with the aim of using them for the pathogenetic therapy of children with congenital ichthyosis.

  • 0 views
  • 17 Aug, 2021
  • 1 location
None
Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis

Psoriasis has been associated with an increasing risk for atherosclerosis. The investigators investigated whether surrogate markers of subclinical atherosclerosis, vascular dysfunction and myocardial dysfunction are impaired in patients with psoriasis compared to normal controls ,coronary artery disease patients and untreated hypertension subjects. The investigators also examined the effect of treatment …

cyclosporine
ustekinumab
apremilast
etanercept
atherosclerosis
  • 0 views
  • 21 Nov, 2021
  • 1 location