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Found 132 clinical trials
Colorectal Metastasis Prevention International Trial 2 (COMPIT-2)

The short perioperative period (days to weeks around surgery) is characterized by stress-inflammatory responses, including catecholamines (CAs, e.g., adrenaline) and prostaglandins (PGs, e.g., prostaglandin-E2) release, and induce deleterious pro-metastatic effects. Animal studies implicated excess perioperative release of CAs and PGs in facilitating cancer progression by affecting the malignant tissue, its …

metastasis
carcinoma
rectal carcinoma
  • 7 views
  • 03 Feb, 2022
  • 1 location
Wearable Devices for Secondary Prevention of Ischemic Stroke

Ischemic stroke is an important cause of death and disability in Western countries. Different risk factors have been identified such as hypertension, diabetes, dyslipidemia, smoke, atrial fibrillation, obesity, and sedentary. The aim of this study is to evaluate the feasibility of an approach based on the use of wearable devices …

stroke
fibrillation
atrial fibrillation
hypertension
diabetes
  • 0 views
  • 28 Feb, 2022
  • 1 location
An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses

The purpose of this study is to pilot and implement a peer mentor intervention focused on overdose prevention and care. The intervention consists of 3 sessions. During the first and second session, each participant will meet individually with a trained staff member. In the 3rd session, the participant will invite …

opiates
Accepts healthy volunteers
heroin
opioid
  • 0 views
  • 21 Mar, 2022
  • 1 location
Antiplatelet Secondary Prevention International Randomised Trial After INtracerebral haemorrhaGe (ASPIRING)-Pilot Phase

ASPIRING is an investigator-led, multicentre, prospective, randomised, open-label, blind outcome (PROBE), parallel group, clinical trial. The pilot phase will explore the feasibility of conducting a trial of starting antiplatelet monotherapy versus avoiding antiplatelet therapy for reducing all serious vascular events for adults surviving symptomatic stroke due to spontaneous intracerebral haemorrhage …

  • 0 views
  • 23 Sep, 2021
  • 2 locations
Effects of an Avocado Based meDiterranean Diet on Serum Lipids for Secondary Prevention After Ischemic StrokE Trial. Study Protocol. (ADD-SPISE)

Recent global burden of disease analysis of DALYs, showed that dietary risk have the highest DALYs in ischemic stroke among behavioral risk factors. The MediDiet is associated with a decreased risk of total mortality as well as stroke incidence and mortality. Although not part of the classical Mediterranean diet they …

body mass index
coronary artery disease
secondary prevention
stroke
heart disease
  • 0 views
  • 04 Feb, 2022
  • 1 location
STroke Secondary Prevention With Catheter ABLation and EDoxaban for Patients With Non-valvular Atrial Fibrillation: STABLED Study

Catheter ablation (CA) has been reported to reduce risk of stroke in patients with nonvalvular atrial fibrillation (NVAF) in retrospective studies, but risk and benefit of CA has not been well elucidated in NVAF with recent cerebral infarction in prospective randomized trials.

  • 0 views
  • 22 Jan, 2021
  • 21 locations
Prevention and Treatment of Pyrrolitinib-associated Diarrhea

In this study, patients taking pyrrolitinib alone or combined with pyrrolitinib were recruited (170 cases of secondary prevention and 300 cases of non-secondary prevention). Non-secondary

  • 0 views
  • 10 Feb, 2021
  • 1 location
T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Background Sometimes breast cancer spreads (metastasizes) to the brain. Researchers want to study new treatments for brain metastases. The drug Temozolomide is approved to treat brain tumors. Researchers want to see if combining it with the drug T-DMI prevents the formation of new metastases in the brain. Objective To study …

brain metastases
HER2
temozolomide
her2/neu-positive breast cancer
mammogram
  • 44 views
  • 17 Jun, 2022
  • 1 location
Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

The aim of the study is to compare the effectiveness of rifaximin versus norfloxacin for secondary prevention of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

cirrhosis
secondary prevention
rifaximin
norfloxacin
ascites
  • 9 views
  • 22 Jan, 2021
  • 1 location
Long-term Follow-up After Stroke (The LAST-long Trial) (LAST-long)

secondary prevention. The primary aim of this project is to evaluate the effectiveness of a multimodal individualized intervention to prevent functional decline in the long term after stroke.

ischemic stroke
recurrent strokes
acute stroke
  • 0 views
  • 07 Feb, 2022
  • 4 locations