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Found 43 clinical trials
Methylphenidate in Childhood Apraxia of Speech

The purpose of this study is to describe the possible effects of methylphenidate (MPH) on speech intelligibility in children with childhood apraxia of speech (CAS) aged 6-12 years. This outcome will be compared between MPH intake and placebo intake.

  • 0 views
  • 14 May, 2022
  • 1 location
Coronary Artery Disease in Patients With Friedreich's Ataxia

Friedreich's ataxia is a debilitating, inherited disease cause by mutations in a protein called frataxin (FXN). FXN is one of several proteins that controls the production of iron-sulfur clusters, molecules that are essential for energy production in our cells as well as repair of our genetic code embedded in DNA …

deficiency
iron
cardiomyopathy
  • 0 views
  • 23 Mar, 2022
  • 1 location
8-Weeks of High-Intensity Interval Training or Concurrent Training in Overweight and Obese Adult Males

Overweight and obesity is becoming increasingly prevalent, constituting 64% of all adults in England, causing an incessant rise in cost to the National Health Service. Exercise and physical activity have the potential to reduce incidence of overweight and obesity, as well as improve obesity-related ill health. However, overweight and obese …

Accepts healthy volunteers
  • 0 views
  • 16 May, 2022
  • 1 location
SpotLight-19 Research & Development Study

In this study, we will use the SpotLight-19 device in patients presenting to a coronavirus disease (COVID-19) Assessment Centre for polymerase chain reaction (PCR) testing. Consenting patients will undergo a Spotlight-19 scan. We will link the scan to PCR results, age, vaccination status, and COVID-19 symptoms in order to calibrate …

Accepts healthy volunteers
  • 0 views
  • 24 Mar, 2022
  • 1 location
Optimized Psycho-oncological Care Through an Interdisciplinary Care Algorithm (OptiScreen)

Adequate, needs-oriented psycho-oncological care contributes to reducing the burden on cancer patients and their relatives and to improving the quality of life. There is still a need for clarification regarding the need and the determination of psychosocial needs. This multi-center study (3 centers: Hanover, Leipzig and Dresden) aims at a …

  • 0 views
  • 16 Mar, 2022
  • 1 location
RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis) (RHEIA)

commercially available surgical bioprosthetic valve. Patients will undergo the following visits: Screening, Procedure, Post Procedure, Discharge, 30 day, 6 months (telephone contact) and 1 year.

exercise test
tavi
stenosis
calcium
aortic valve replacement
  • 94 views
  • 24 Mar, 2022
  • 28 locations
Screening for Cancer in Patients With Unprovoked VTE

Open and multicenter randomized clinical trial (1:1) comparing limited screening with extended screening with the performance of Positron emission tomography-computed tomography (PET-CT) scan in the search for neoplasms in patients with unprovoked venous thromboembolic disease at high risk of developing cancer at follow-up. Introduction: Cancer screening in patients with unprovoked …

deep venous thrombosis of lower extremity
deep vein thrombosis
thrombosis
venous thromboembolic disease
cancer
  • 0 views
  • 18 Dec, 2021
  • 9 locations
Case-finding Study to Detect and Quantify Episodes of Absolute Arrhythmia Using an Automated Wearable Monitoring System

This feasibility study will develop and evaluate pathways to identify participants with wearable-detected absoulute Arrhythmia (AA) and to enable local study teams to contact them regarding participation in a controlled trial of oral anticoagulation in this population, which will be conducted after the feasibility study.

  • 0 views
  • 16 Mar, 2021
  • 2 locations
The Effectiveness of a CA-CBI on Psychological Distress of University Students During the COVID-19 Pandemic

university students' psychological distress and increase their well-being during the COVID-19 pandemic. Potential participants will be given an informed consent and included in a screening procedure to

Accepts healthy volunteers
  • 0 views
  • 22 Mar, 2022
  • 1 location
Efficacy of an Adapted Multicomponent Physical Activity Intervention to Reduce Psychosocial Distress in Rural Adults Following Cancer Diagnosis

This study is to adapt and evaluate a multicomponent intervention to reduce sedentary behavior and improve psychosocial distress and quality of life in rural cancer survivors currently receiving treatment. The multicomponent intervention combines Harmony & Health (HH),40,41 a face-to-face light-intensity physical activity intervention to reduce sedentary behavior and psychosocial distress, …

  • 0 views
  • 05 Oct, 2021
  • 1 location