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Found 120 clinical trials
Featured trial
Study to evaluate HZN-825 in patients with Diffuse Cutaneous Systemic Sclerosis (dcSSc)

The goal is to determine the efficacy, safety and tolerability for 300 patients with Diffuse Cutaneous Systemic Sclerosis (dcSSc) assigned to either one of 2 dose regimens of HZN-825

MRSS
raynaud's syndrome
raynaud's phenomenon
rheumatism
diffuse cutaneous systemic sclerosis
  • 31 views
  • 17 Sep, 2023
  • 85 locations
Featured trial
A phase 3, randomized, placebo-controlled study to assess the efficacy and safety of an investigational medication versus placebo in patients with systemic sclerosis

A phase 3, randomized, placebo-controlled study to assess the efficacy and safety of an investigational medication versus placebo in patients with systemic sclerosis

  • 1219 views
  • 23 Nov, 2020
  • 1 location
Featured trial
Digital biomarkers for Alzheimer's Disease with compact dual-mode brain sensing

The research team is conducting a research study to find biological signs in the brain for early detection of Alzheimer’s Disease (AD) with a new low-cost, portable device. This study plans to use two modern brain scanning devices to detect (1) your forehead blood flow and metabolism using an optical …

Accepts healthy volunteers
  • 0 views
  • 28 Mar, 2023
  • 1 location
Featured trial
A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

A 12-month, Randomized, Rater- and Dose-blinded Study to Compare the Efficacy and Safety of Fingolimod 0.25 mg and 0.5 mg Administered Orally Once Daily With Glatiramer Acetate 20 mg Administered Subcutaneously Once Daily in Patients With Relapsing-remitting Multiple Sclerosis

  • 248 views
  • 25 Mar, 2021
  • 1 location
A Study in People With Systemic Sclerosis to Test Whether BI 685509 Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms

sclerosis. Systemic sclerosis is also called scleroderma. The purpose of this study is to find out whether a medicine called BI 685509 helps people with scleroderma who have symptoms due to lung

  • 0 views
  • 19 Sep, 2023
  • 127 locations
Opioid Treatment and Peer Recovery Support (JCOIN)

Determine whether a facilitated local change team intervention improves a probation organization's client-level medication for opioid use disorder (MOUD) outcomes and implementation outcomes relative to baseline across multiple sites. Determine whether client-level outcomes are further enhanced by the introduction of Peer Support Services.

  • 0 views
  • 14 Mar, 2022
  • 3 locations
Italian Digital Primary Cardiovascular Prevention Study (CV-PREVITAL)

The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular (CV) risk factors (in the short term) and the occurrence of vascular events (in the long term). Promoted …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 29 locations
Effect of the Use of Specific Oral Hygiene Devices on Gingival Health Among Patients With Systemic Sclerosis (ScleroBross)

Systemic sclerosis is a rare multisystem connective-tissue disorder characterized by three major pathological hallmarks: widespread fibrosis, vasculopathy and immunological abnormalities. This

fibrosis
vascular disease
  • 0 views
  • 26 Aug, 2023
  • 1 location
New Clinical End-points in Patients With Primary Sjögren's Syndrome (NECESSITY)

There are no approved treatments for pSS and the clinical endpoints currently used in clinical trials are inadequate to capture all aspects of the disease that should be evaluated in clinical

  • 4 views
  • 14 May, 2022
  • 1 location
Self-management of Stress and Sleep Disturbances With Virtual Reality Relaxation (Relax XL)

Stress is a well-established factor in the onset and continuation of burn-out anxiety, mood and psychotic disorders. Furthermore, sleep disturbances predispose and exacerbate mental health symptoms of the condition. In people with mental health problems, higher (social) stress-reactivity and impaired stress-recovery are present which is further aggravated by sleep disturbances …

  • 0 views
  • 04 Oct, 2022
  • 2 locations