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Found 61 clinical trials
Longitudinal Analysis of Mental Disorders, Psychosocial Distress and Care Needs of Patients and Their Relatives (LUPE)

representative of the German overall population. All participants will receive validated self-report questionnaires. Cancer patients will be interviewed using the standardized clinical interview SCID-5

solid tumor
primary cancer
  • 30 May, 2022
  • 1 location
Evaluation of Patients With Immune Function Abnormalities

severe combined immunodeficiency (XSCID), chronic granulomatous disease (CGD), and leukocyte adhesion deficiency (LAD), or conditions resulting from outside factors, such as graft-versus-host disease

Accepts healthy volunteers
  • 24 Jul, 2022
  • 1 location
The Mechanistic Biology of Primary Immunodeficiency Disorders

Background Primary immunodeficiency disorders, or PIDs, are diseases that weaken the immune system. This makes it easier for a person to get sick. Some PIDs are mild and may not be diagnosed until later in life. Other kinds are severe and can be identified shortly after birth. Researchers want to …

severe combined immunodeficiency
Accepts healthy volunteers
  • 27 Jul, 2022
  • 2 locations
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry

While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve the delivery of care and the quality of outcomes for youths, adults and seniors with depression across the Maritimes. The investigators …

depressed mood
psychiatric disorder
  • 23 Jan, 2021
  • 1 location
Registry Study of Revcovi Treatment in Patients With ADA-SCID

This registry is conducted in patients with adenosine deaminase severe combined immune deficiency (ADA-SCID) treated with Revcovi™ to collect periodic clinical and biochemical data on safety and

adenosine deaminase
ada deficiency
  • 10 Aug, 2022
  • 10 locations
Genetic Basis of Immunodeficiency

This study will examine the role of hereditary factors in different forms of severe combined immunodeficiency (SCID). Patients with immunodeficiencies may be eligible for this study

  • 29 Jul, 2022
  • 1 location
Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products

This protocol (GENEFU) provides a mechanism for the 15-year followup period that the FDA requires for all participants in gene transfer protocols and assures that adequate followup can be maintained for a wide variety of participants on different individual gene therapy protocols at St. Jude Children's Research Hospital. GENEFU serves …

blood disorder
neurological disorder
second malignancies
late effects
primary cancer
  • 23 Jan, 2022
  • 1 location
Metabolic Profiling of Immune Responses in Immune-mediated Diseases

Background The immune system is the part of the body that fights infection. Some people have immune deficiencies that cause skin rashes, make them get sick often with infections, or make it difficult for their skin to heal. Researchers want to learn more to better treat conditions that affect immune …

Accepts healthy volunteers
  • 22 Jul, 2022
  • 1 location
Survey on Patients After Childbearth Following Bariatric Surgery (SPOtMom)

Women with a history of bariatric surgery may face various difficulties during pregnancy and puerperal time. Therefore it is assumed the prevalence of mental health disorders might be higher than in average women during and after pregnancy. This could possibly lead to an unsatisfying weight progress and therapeutic non-adherence. These …

  • 21 Mar, 2022
  • 1 location
The Neural Bases of Emotion Regulation in Bulimia Nervosa

This project aims to explore emotional processing and regulation in individuals with Bulimia Nervosa (BN) with a view to better understand its underlying causes. Previous research suggests that binge eating and purging behaviours may be linked to difficulties with emotions and impulses. However, most of the research has been conducted …

Accepts healthy volunteers
eating disorder
bulimia nervosa
  • 14 Jul, 2022
  • 1 location