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Found 60 clinical trials
rTMS Response Trajectories in Depression

Previous studies on network mechanism of repetitive transcranial magnetic stimulation (rTMS) suggest that pretreatment resting-state functional magnetic resonance imaging (rs-fMRI) connectivity may serve as a predictive biomarker for antidepressant treatment response. In phase I of the study, the focus was on the predictive value of pretreatment connectivity between the left …

major depressive disorder
depressed mood
transcranial magnetic stimulation
psychiatric disorder
  • 24 Jan, 2021
  • 1 location
Internet-based Cognitive Behavioral Therapy for Chronic Tic Disorder and Tourette's Disorder: a Feasibility Trial

Tic disorders, including Tourette's Disorder (TD) and Chronic Motor or Vocal Tic Disorder (CTD), are neurodevelopmental motor disorders characterised by motor and/or vocal tics. TD/CTD are impairing conditions with onset during childhood that often persist into adulthood. Behaviour therapy (BT) is an effective treatment for TD/CTD and is recommended as …

  • 09 Jun, 2021
  • 1 location
Neonatal Screening of Severe Combined Immunodeficiencies

The goal of the proposed research is to observe the prevalence and establish the validity of a newborn screening method for severe combined immunodeficiency (SCID). The assay to be used is

severe combined immunodeficiency
  • 03 Feb, 2021
  • 1 location
Participation in a Research Registry for Immune Disorders

Background People with primary immune deficiency diseases (PIDD) have weak immune systems. This makes it hard for their bodies to fight infection. The Immune Deficiency Foundation has a network to collect data about people with PIDD. It is called the United States Immunodeficiency Network. It will help doctors and scientists …

primary immunodeficiency
  • 28 Jun, 2021
  • 1 location
Genetic Analysis of Immune Disorders

The purposes of this study are to 1) identify the genes responsible for certain immune disorders, 2) learn about the medical problems they cause, and 3) learn how to predict who is likely to develop these disorders and what the risk is of passing them on to children. The immune …

local anesthetic
wbc count
  • 15 Sep, 2021
  • 1 location
Target Therapies Resistance Molecular Profiling in Patients With Neoplastic Disease

, blood and vital tumor tissue derived form surgical or biopsy procedures. Whereas possible, vital tumor specimens will be inoculated and propagated in immunocompromised NOD/SCID mice to study the genetic

lung cancer
liver metastasis
breast cancer
  • 21 Jan, 2021
  • 10 locations
Evaluation of Patients With Immune Function Abnormalities

severe combined immunodeficiency (XSCID), chronic granulomatous disease (CGD), and leukocyte adhesion deficiency (LAD), or conditions resulting from outside factors, such as graft-versus-host disease

  • 09 Jul, 2021
  • 1 location
Longitudinal Analysis of Mental Disorders Psychosocial Distress and Care Needs of Patients and Their Relatives

representative of the German overall population. All participants will receive validated self-report questionnaires. Cancer patients will be interviewed using the standardized clinical interview SCID-5

  • 27 Jan, 2021
  • 1 location
The Mechanistic Biology of Primary Immunodeficiency Disorders

Background Primary immunodeficiency disorders, or PIDs, are diseases that weaken the immune system. This makes it easier for a person to get sick. Some PIDs are mild and may not be diagnosed until later in life. Other kinds are severe and can be identified shortly after birth. Researchers want to …

severe combined immunodeficiency
  • 15 Sep, 2021
  • 2 locations
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry

While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve the delivery of care and the quality of outcomes for youths, adults and seniors with depression across the Maritimes. The investigators …

depressed mood
psychiatric disorder
  • 23 Jan, 2021
  • 1 location