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Found 398 clinical trials
Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)

To compare two evidence-based treatments, Cognitive Enhancement Therapy (CET) and Social Skills Training (SST) that have been shown in meta-analyses and in our own research to be effective to improve community functioning. The investigators will test the impact of CET and SST on community functioning, with special attention to their …

  • 0 views
  • 19 Apr, 2022
  • 4 locations
Evoked Responses as Pharmacodynamic Biomarkers in Healthy and Schizophrenic Participants (MK-4334-007)

participants with schizophrenia (SZ) of mild-to-moderate severity to determine if the mean inter-trial coherence (ITC) magnitude derived from the 40 Hz-ASSR is lower in SZ than in HC at baseline.

Accepts healthy volunteers
  • 0 views
  • 28 Jun, 2022
  • 2 locations
Acceptance and Commitment Therapy-based Lifestyle Counselling Programme for Early Psychosis on Physical Activity

This pilot randomized controlled trial aims to determine the feasibility, acceptability and preliminary effects of an Acceptance and Commitment Therapy-based Lifestyle Counselling Programme (ACT-LCP) on the physical and psychosocial health outcomes of patients with early psychosis over a 12-week follow-up.

  • 1 views
  • 04 Sep, 2021
  • 1 location
Plan D- Vitamin D Supplementation in Psychotic Disorders

Background: Impairment in cognitive processing speed is a consistent finding in schizophrenia spectrum disorder. Vitamin D deficiency is found to be significantly associated with reduced

  • 0 views
  • 26 Apr, 2022
Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands

The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are

Accepts healthy volunteers
  • 10 views
  • 25 Mar, 2022
  • 1 location
Effects of Methylphenidate on Brain and Cognition in 22q11 Deletion Syndrome

Chromosome 22q11.2 deletion syndrome (22q11DS) is a neurogenetic condition associated with a high risk of psychiatric disorders, including schizophrenia spectrum disorders. This population is

  • 0 views
  • 21 Apr, 2022
  • 1 location
Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders

To explore the whole-brain anatomical and functional abnormalities in drug-naive patients with schizophrenia ,drug-naive patients with BD, drug-naive patients with MDD and healthy controls by

  • 0 views
  • 25 Jan, 2021
  • 1 location
Hippocampal Response to Acute Oral Doses of CBD During an fMRI Memory Task

drug (CBD versus placebo) in patients who have been diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder with psychosis compared to healthy controls.

Accepts healthy volunteers
  • 0 views
  • 29 May, 2022
  • 1 location
Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes

Schizophrenia is a life long illness, the management of its early stage is the key in its long term outcomes. The early stage of schizophrenia includes the prodromal and first episode, during

  • 0 views
  • 02 May, 2021
  • 3 locations
Evaluation of tDCS Efficacy in Enduring Anorexia Nervosa

schizophrenia. The objectives of the study will be to evaluate the efficacy of tDCS in anorexia nervosa resistant to conventional treatments on weight gain, eating behavior, psychological and

  • 0 views
  • 07 Aug, 2021
  • 4 locations