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Found 286 clinical trials
SV2 PET Imaging With [11C]APP311 (SV2)

The aim of this study is to evaluate a new SV2A tracer, [11C]APP311, in healthy aging and neuropsychiatric disorders including psychotic disorders and cannabis use disorders.

Accepts healthy volunteers
  • 04 Oct, 2022
  • 1 location
Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.

The DUNDRUM Forensic Redevelopment Evaluation study (D-FOREST study) is a multi-site comprehensive evaluation of a complete National Forensic Mental Health Service. The study will have a prospective, observational, longitudinal design which will permit the evaluation of benefit over time for individual patients, groups of patients and the evaluation of the …

  • 20 Oct, 2021
  • 1 location
Counterfactual Thinking in Amyotrophic Lateral Sclerosis (CFTSLA)

neurological, neurodegenerative and psychiatric conditions, such as Huntington's disease, Parkinson's disease, prefrontal cortex damage, schizophrenia, obsessive-compulsive disorder and major depressive

Accepts healthy volunteers
  • 09 Apr, 2023
  • 1 location
A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty

, schizophrenia, and substance abuse. Many of these sex differences emerge during or shortly after puberty and are maintained until the 5th-6th decade of life. For example, the two-fold greater risk of unipolar

Accepts healthy volunteers
  • 06 Apr, 2023
  • 1 location
Objective Assessment of Behavioral Associations of Patients With Dementia

It is generally acknowledged that patients with dementia are best cared for at home. However, outbursts of various behavioral disturbances, e.g., combativeness, appear in most cases and often necessitate institutionalization. These outbursts are often without apparent warning, which limits preventive interventions. The measurement of the electrical activity of the skin …

behavioral problems
Accepts healthy volunteers
cognitive assessment
behavioral disturbances
  • 20 Apr, 2022
  • 1 location
Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders

The aim of this pilot intervention is to examine the acceptability of a harm reduction intervention approach to tobacco use for individuals with serious behavioral health disorders and its association with a decrease in smoking. The intervention uses a "dynamic" approach to patient choice, allowing participants the option to explore …

nicotine dependence
substance use
nicotine product
  • 04 Oct, 2021
  • 1 location