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Found 4 clinical trials
Sapanisertib Carboplatin and Paclitaxel in Treating Patients With Recurrent or Refractory Malignant Solid Tumors

This phase I trial studies the sides effects and best dose of sapanisertib, carboplatin, and paclitaxel in treating patients with malignant solid tumors that have come back (recurrent) or do not

solid tumor
glycosylated hemoglobin
neutrophil count
sapanisertib
metastasis
  • 25 views
  • 24 Jan, 2021
  • 2 locations
Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

This phase I trial studies the side effects and best dose of sapanisertib and metformin in treating patients with cancers that have spread to other parts of the body (advanced/metastatic), have

glycosylated hemoglobin
neutrophil count
liver metastasis
metastasis
sapanisertib
  • 0 views
  • 23 Jan, 2021
  • 2 locations
Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

This phase I/Ib trial studies the side effects and best dose of CB-839 HCl when given together with sapanisertib in treating patients with non-small cell lung cancer that has spread to other

brain imaging
chronic hepatitis b
neutrophil count
sapanisertib
brain metastases
  • 0 views
  • 02 Jun, 2021
  • 1 location
Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

This phase Ib trial studies the best dose, safety, and effect of alisertib or sapanisertib, in combination with osimertinib, in treating patients with EGFR mutated stage IIIB or IV non-small

neutrophil count
sapanisertib
measurable disease
lung cancer
recurrent non-small cell lung cancer
  • 0 views
  • 11 Apr, 2021