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Found 4 clinical trials
Sapanisertib Carboplatin and Paclitaxel in Treating Patients With Recurrent or Refractory Malignant Solid Tumors

This phase I trial studies the sides effects and best dose of sapanisertib, carboplatin, and paclitaxel in treating patients with malignant solid tumors that have come back (recurrent) or do not

tumor cells
solid tumor
seizure disorder
metastasis
mammogram
  • 25 views
  • 24 Jan, 2021
  • 2 locations
Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

This phase I trial studies the side effects and best dose of sapanisertib and metformin in treating patients with cancers that have spread to other parts of the body (advanced/metastatic), have

tumor cells
metastasis
diabetes
hba1c
neutrophil count
  • 0 views
  • 23 Jan, 2021
  • 2 locations
Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

This phase I/Ib trial studies the side effects and best dose of CB-839 HCl when given together with sapanisertib in treating patients with non-small cell lung cancer that has spread to other

tumor cells
immune checkpoint inhibitor
hepatitis c virus
keap1
brain imaging
  • 0 views
  • 25 Jan, 2021
  • 1 location
Osimertinib With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer

This phase Ib trial studies the side effects and best dose of alisertib or sapanisertib, in combination with osimertinib, in treating patients with EGFR mutated stage IIIB or IV non-small cell

tumor cells
stereotactic body radiation therapy
EGFR
lactational amenorrhea
pd-l1
  • 0 views
  • 25 Jan, 2021