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Found 76 clinical trials
Phase II Trial of Tirelizumab Combined With R2-ICE Regimen in the Treatment of rrDLBCL/HGBL

This study was a prospective, multi-center, single-arm, Phase II clinical study. Compared with the literature data, objective response rate (ORR) and complete response rate (CR) were the primary endpoint, and 1-year and 2-year progression-free survival (PFS) and 2-year overall survival (OS) were the secondary endpoint. To evaluate the efficacy and …

  • 0 views
  • 30 Sep, 2021
  • 1 location
HFHS-1801-A Pilot Study of Immunotherapy as Consolidation Therapy for Patients With Recurrent Head and Neck Cancer

The study is a pilot study to explore the feasibility and efficacy of immunotherapy following salvage surgery for recurrent head and neck cancer.

carcinoma
head and neck cancer
recurrent head and neck carcinoma
squamous cell carcinoma of head and neck
cancer
  • 0 views
  • 19 Feb, 2022
  • 1 location
Compare Efficacy of CHOP Versus Fractionated ICED in Transplant-eligible Patients With Previously Untreated PTCL

This study is a Randomized Phase II Study to Compare Efficacy of CHOP versus Fractionated ICED in Transplant-eligible Patients with Previously Untreated Peripheral T-cell Lymphoma.

dexamethasone
prednisone
peripheral t-cell lymphoma
enteropathy
anaplastic large cell lymphoma
  • 10 views
  • 26 Jan, 2021
  • 1 location
Stereotactic Boost and Long-Term Androgen Deprivation for Adenocarcinoma of the Prostate

We hypothesize that Stereotactic Body Radiotherapy Boost (SBRT) as a boost to the prostate following whole pelvic intensity modulated radiotherapy (IMRT) can be delivered effectively and safely in a population of men with unfavorable intermediate and high risk localized prostate cancer. Our primary objective is to assess the feasibility and …

endocrine therapy
androgens
cancer
leuprolide
hormone therapy
  • 6 views
  • 06 Oct, 2021
  • 1 location
The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases? (CyberChallenge)

Patients suffering from malignancies in advanced stages often develop brain metastases, which limit both the life span and the quality of life. Therapy options for multiple brain metastases may vary and range from stereotactic radiosurgery (SRS), whole-brain radiotherapy (WBRT), chemotherapy, immunotherapy to palliative best supportive care. Especially the efficacy and …

cancer chemotherapy
brain metastases
  • 0 views
  • 29 May, 2022
  • 1 location
Study of Efficacy and Safety of Flumatinib Combined With Chemotherapy in Ph Positive ALL

Philadelphia chromosome (BCR-ABL1, Ph) is the most common genetic abnormality in acute lymphoblastic leukemia (ALL) and an independent prognostic risk factor. With the increase of age, the incidence of patients over 60 years old can reach 50%, whose 5-year overall survival rate was less than 20%. With the application of …

benzene ring
prednisone
imatinib
tyrosine
philadelphia chromosome
  • 0 views
  • 08 Apr, 2022
  • 1 location
Treatment of HOsPitalised Inpatients for Hepatitis C (TOPIC): Therapeutic Intervention Enhancing Care Linkage in People Who Inject Drugs (TOPIC)

This study will evaluate the proportion of patients achieving confirmed SVR12 (undetectable HCV RNA at time point 12 weeks plus post treatment commencement) in patients hospitalised for IRID (injecting related infectious diseases) and commencing inpatient DAA treatment within public hospital services.

glecaprevir/pibrentasvir
treatment regimen
hepatitis
sofosbuvir
fibroscan
  • 0 views
  • 22 Apr, 2022
  • 1 location
Intraoperative Radiotherapy After the Resection of Brain Metastases (INTRAMET)

INTRAMET examines prospectively the effectiveness of an intraoperative radiotherapy immediate after the surgical resection of brain metastases. Patients won't receive further radiation therapy of the intraoperatively treated lesion.

metastasis
  • 5 views
  • 19 Jun, 2022
  • 1 location
Disulfiram and Cisplatin in Refractory TGCTs. (DISGCT)

Non-randomized, open-label, single center trial to assess efficacy (as measured by overall response rate (ORR) by RECIST 1.1 of disulfiram and cisplatin in patients with multiple relapsed/refractory germ cell tumors (GCTs).

measurable disease
platelet count
major surgery
cancer chemotherapy
cancer
  • 15 views
  • 08 Feb, 2022
  • 1 location
Pilot Study of Early Postoperative Fractional Ablative Laser Treatment of Skin Grafts for Burns

Doctors and patients refer to all areas of skin changes from burn injury as burn scars. However, different areas of scars from burns can be treated differently. The burn scars that come from skin grafting surgery might be improved with laser treatment. The purpose of this study is to see …

  • 0 views
  • 17 Sep, 2022
  • 1 location