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Found 76 clinical trials
Use of Quantitative Ultrasound to Guide Adaptive Chemotherapy Among Women With Breast Cancer

therapies could be switched to more efficacious treatments or aggressive salvage therapy which has shown to already benefit patients. The overarching goal of this research is to transform the delivery of

  • 0 views
  • 14 Feb, 2022
Performance of Prostate MRI and Following Biopsy to Detect Prostate Cancer Recurrence After Focal Therapy (IRMProft)

recurrence, pre-biopsy and preoperative mapping for an eventual salvage therapy. However, question about the performance of MRI and targeted biopsy in monitoring and defining successful therapy and follow up

  • 0 views
  • 22 Apr, 2022
  • 7 locations
Comparing "Salvage" Radiotherapy and Individualized PSMA PET/CT Targeted Treatment in With Relapsing Prostate Cancer

/CT. The control group receives standard salvage therapy and the result of the PET/CT is blinded. The patients are followed-up with PSA test and quality of life questionnaires.

  • 0 views
  • 01 Oct, 2021
  • 5 locations
Study of Isatuximab and Cemiplimab in Relapsed or Refractory Natural Killer/T-cell Lymphoid Malignancy

of ENKTL and ANKL. In addition, the proven efficacy of pembrolizumab in relapsed or refractory ENKTL support the use of PD1 inhibitor as a salvage therapy for this disorder. The addition of

  • 0 views
  • 01 Oct, 2021
  • 1 location
Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

radiation or both. All patients experience a recurrence after first-line therapy, so improvements in both first-line and salvage therapy are critical to enhancing quality-of-life and prolonging survival. It

anaplastic astrocytoma
karnofsky performance status
brain tumor
astrocytoma, anaplastic
avastin
  • 146 views
  • 05 Nov, 2021
  • 1 location
A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol

treatment based on the physician's experience. An effective salvage therapy is essential for this high-risk group. For 91without RO involvement (RO-), 78 patients (85.7%) were rapid responders at

  • 0 views
  • 06 Mar, 2021
  • 1 location
Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or Clonal Cytopenia of Undetermined Significance

This phase II trial studies the effect of ascorbic acid and combination chemotherapy in treating patients with lymphoma that has come back (recurrent) or does not respond to therapy (refractory) or clonal cytopenia of undetermined significance. Ascorbic acid may make cancer cells more sensitive to chemotherapy. Drugs used in chemotherapy, …

conjugated bilirubin
salvage therapy
combination chemotherapy
gemcitabine
platelet count
  • 17 views
  • 15 Jun, 2022
  • 2 locations
A Two Week Nitazoxanidebased Quadruple Regimen

Helicobacter pylori (H. pylori) infection is a global health problem as it is associated with peptic ulcers, chronic gastritis, duodenitis, and stomach cancer. Therefore, the eradication of the pathogen is of critical importance to reduce H. pylori-related complications . However, due to increasing antibiotic resistance, eradication of Helicobacter pylori has …

peptic ulcer
omeprazole
doxycyclin
cancer
clarithromycin
  • 0 views
  • 22 Jan, 2021
  • 1 location
Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer (PROMPT)

Prostate cancer is the second most common cancer among Canadian men of which approximately 20-30% present with high-risk tumour characteristic. Although surgery can be curative in patients evidencing pathological high-risk disease (extracapsular extension, seminal vesicle involvement, positive surgical margins), a large proportion will develop biochemical failure within years from the …

metastasis
prostate specific antigen
immunological adjuvant
testosterone
adenocarcinoma of prostate
  • 3 views
  • 25 Feb, 2022
  • 2 locations
Immuno-Oncology Drugs Elotuzumab Anti-LAG-3 and Anti-TIGIT

This a Phase I/II randomized trial for patients with relapsed refractory Multiple Myeloma who have relapsed after treatment with prior therapies. The protocol is designed to evaluate two agents, Anti-LAG-3 and Anti-TIGIT, in order to understand their immunologic effects and safety both as single agents and in combination with pomalidomide …

growth factor
proteasome inhibitor
elotuzumab
immunoglobulins
cancer
  • 0 views
  • 19 Sep, 2021
  • 8 locations