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Found 98 clinical trials
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Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer

This phase I trial studies the side effects and best dose of ruxolitinib phosphate when given together with pembrolizumab in treating patients with stage IV triple negative breast cancer that

estrogen
cancer chemotherapy
platelet count
progesterone receptor
erbb2
  • 42 views
  • 05 Jun, 2021
  • 1 location
None
PTCy and Ruxolitinib vs PTCy Tacrolimus and MMF in MUD and Haploidentical HSCT

versus ruxolitinib after post-transplant cyclophosphamide. In total 128 patients will be included in the study. After inclusion into the study and performing of transplantation patients will be

  • 0 views
  • 27 Jan, 2021
  • 2 locations
None
Ruxolitinib for Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplantation (HCT)

This research study is studying a drug as a possible treatment for Bronchiolitis Obliterans Syndrome (BOS) after having an Allogeneic Hematopoietic Cell Transplantation (HCT).

  • 1 views
  • 10 Oct, 2021
None
Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion

This study is to find out if treating Chronic Myelomonocytic Leukemia (CMML) with a study drug (ruxolitinib) can improve outcomes of patients with CMML.

chronic myelomonocytic leukemia
myeloproliferative disorder
  • 4 views
  • 22 Aug, 2021
  • 4 locations
None
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)

The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.

  • 0 views
  • 01 Apr, 2021
  • 6 locations
None
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

This phase II trial studies how well ruxolitinib works in treating patients with hypereosinophilic syndrome or primary eosinophilic disorders.

  • 0 views
  • 26 Nov, 2021
  • 2 locations
None
Ruxolitinib and Chidamide for Acute T Cell Lymphoblast Leukemia/ Lymphoblastic Lymphoma

The purpose of this study is to determine the efficacy and safety of Ruxolitinib and Chidamide intensified conditioning regimen in patients with Acute T cell Lymphoblast leukemia/ lymphoblastic

  • 0 views
  • 21 Oct, 2021
  • 1 location
None
A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy

The study is a designed to evaluate safety and activity of APG-1252 when administered as monotherapy and in combination with ruxolitinib in previously ruxolitinib treated myelofibrosis patients

  • 0 views
  • 26 Jan, 2021
  • 1 location
None
The Effectiveness of Patient-tailored Treatment in Patients With (Sub)Acute Neck Pain

The purpose of this study is to assess the safety, tolerability, and efficacy of BMS-986158 alone and in combination with either Ruxolitinib or Fedratinib in participants with Dynamic

arm pain
neck exercises
cancer
manual therapy
  • 0 views
  • 02 Dec, 2021
  • 1 location
None
LCI-HEM-MYE-CRD-004 (MMRC-073 CARJAK): Study of CRD for Carfilzomib-Refractory Multiple Myeloma

The primary objective of Phase I is to establish the maximum tolerated dose (MTD) of ruxolitinib in combination with carfilzomib and dexamethasone. The primary objective of phase II is to

platelet count
neutrophil count
dexamethasone
measurable disease
monoclonal antibodies
  • 19 views
  • 01 Oct, 2021
  • 2 locations