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Found 104 clinical trials
Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

This is a Phase I/II, multicenter, open-label, dose escalation/dose-expansion study to evaluate the tolerability, safety, and the maximum tolerated dose (MTD) of ruxolitinib when given with

classical hodgkin lymphoma
brentuximab
autograft
measurable disease
graft versus host disease
  • 39 views
  • 21 Mar, 2022
  • 3 locations
Jaktinib Hydrochloride for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

With Ruxolitinib. The experiment is divided into two parts: dose exploration and extended research.

conjugated bilirubin
anemia
platelet count
colony stimulating factor
neutrophil count
  • 22 views
  • 24 Jun, 2021
  • 1 location
A Study of Ruxolitinib and Duvelisib in People With Lymphoma

This study will test the safety of ruxolitinib, given at one dose that does not change, and duvelisib, given at different doses, to find out what effects, if any, the study treatment has on

peripheral t-cell lymphoma
flow cytometry
adult t-cell leukemia/lymphoma
leukemia
platelet count
  • 2 views
  • 08 Aug, 2022
  • 9 locations
Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant (HSCT)

fibrosis has occurred and lesions are irreversible. The hypothesis for this interventional trial is that early treatment with standard Flovent/montelukast and steroids plus ruxolitinib will reverse

  • 0 views
  • 26 Mar, 2022
  • 1 location
MaaT013 as Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients (ARES)

MaaT013 showed interesting results in steroids and ruxolitinib-resistant aGVHD patients with gut involvement (55% ORR at D28) and 47% and 39% OS at 6 and 12 months respectively (Malard 2020

  • 0 views
  • 08 Jul, 2022
  • 18 locations
Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

The purpose of this study is to test how well the drug works, safety and tolerability of an investigational drug called Ruxolitinib in gliomas and glioblastomas, when combined with standard

methylated
cancer
glioblastoma multiforme
malignant brain tumor
oligodendroglioma, anaplastic
  • 41 views
  • 11 Aug, 2022
  • 2 locations
Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma

The purpose of this research study to find out if the drug trametinib in combination with ruxolitinib is safe, tolerable and has beneficial effects in people who has certain type of cancers

liver metastasis
adenocarcinoma
measurable disease
neutrophil count
cancer
  • 11 views
  • 03 Jul, 2022
  • 1 location
Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease

imbalance of the donor immune system in the host. The purpose of this research is to learn more about ruxolitinib as a treatment for both acute and chronic GVHD. Specifically, the investigators

  • 0 views
  • 23 Apr, 2022
  • 1 location
Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

This phase II trial studies how well ruxolitinib works in treating patients with hypereosinophilic syndrome or primary eosinophilic disorders.

  • 0 views
  • 26 Nov, 2021
  • 2 locations
Ruxolitinib and Chidamide for Acute T Cell Lymphoblast Leukemia/ Lymphoblastic Lymphoma

The purpose of this study is to determine the efficacy and safety of Ruxolitinib and Chidamide intensified conditioning regimen in patients with Acute T cell Lymphoblast leukemia/ lymphoblastic

  • 0 views
  • 22 Dec, 2021
  • 1 location