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Found 77 clinical trials
Comparing 150cm OAGB With 150cm Biliopancreatic Limb RYGB. A Non-inferiority Trial (Roux-en-WHY?)

The purpose of this study is to assess the safety and efficiency of OAGB compared to RYGB

gastric bypass
  • 21 Mar, 2022
  • 1 location
Empagliflozin for the Treatment of Postprandial Hypoglycemia

This randomized trial is to test whether a treatment with empagliflozin is superior to placebo in patients with postprandial hypoglycemia after bariatric surgery, that is if it improves health related quality of life (mentally or physically) or reduces the risk of hypoglycemic events.

  • 26 Nov, 2021
  • 3 locations
Surgical or Medical Treatment (ST2OMP)

This study will test the hypothesis that metabolic bariatric surgery will be more effective at providing durable glycemic control and reduce co-morbidities than intensive medical therapy in youth with type 2 diabetes.

sleeve gastrectomy
glucagon-like peptide-1
type 2 diabetes mellitus
  • 21 Jul, 2022
  • 2 locations
Metabolism and Bariatric Surgery Study

The purpose of this study is to determine if diet-induced weight loss causes different changes in hormones that control appetite and glucose control than surgery-induced weight loss. The overall research plan is a non-randomized prospective study of 3 different weight loss (WL) interventions and a lean and an obese healthy …

gastric bypass
calorie diet
bariatric surgery
sleeve gastrectomy
  • 14 May, 2021
  • 1 location
The Importance of Ghrelin for Glucose Metabolism After Sleeve Gastrectomy

The overall aim is to delineate the contribution of ghrelin to glucose tolerance after sleeve gastrectomy. The hypothesis is that decreased concentration of ghrelin after SG is of importance for improved insulin secretion and glucose tolerance seen after SG. The expectation is therefore that infusion of ghrelin will impair insulin …

Accepts healthy volunteers
  • 25 Mar, 2022
Preliminary Efficacy Analysis of Cheng's Giraffe Reconstruction After Proximal Gastrectomy

In the past years, the adenocarcinoma of the esophagogastric junction (AEG) has been increasing obviously in China. It may be caused by the reason of increased body weight, alcohol consumption, gastroesophageal reflux disease and premalignant. In western countries, the 5-year rate of advanced AEG was less than 30%, it was …

  • 26 Jan, 2021
  • 1 location
Bariatric Surgery for the Reduction of cArdioVascular Events Feasibility Trial

Pilot multicentre, open-label, parallel-arm randomized controlled trial (RCT) of 60 patients to demonstrate the feasibility of enrolling patients with high-risk cardiovascular disease (CVD) into an RCT of bariatric surgery versus medical weight management (MWM).

transient ischemic attack
coronary disease
body mass index
  • 04 Feb, 2021
  • 1 location
Pharmacokinetics of Simvastatin Post Laparoscopic Sleeve Gastrectomy (LSG)

This study aims to investigate the change in systemic exposure of simvastatin post LSG.

  • 24 Apr, 2022
  • 1 location
The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric Surgery

This study explores the effects of probiotic administration on the outcomes of surgical treatment, and also on the state of the intestinal microbiota and the intestinal barrier. The study protocol is designed as a randomized double-blind placebo-controlled clinical trial. Patients qualified for bariatric surgery will be randomized to receive probiotics …

  • 17 Jun, 2022
  • 1 location
Comparison of Three Hypoabsortive Surgical Techniques for Treatment of Type IV Morbid Obesity

Morbid obesity is the first non-traumatic cause of death in the western population and it is also progressively beginning to affect the developing countries. Bariatric surgery provides better results than pharmacological treatments and lifestyle changes, granting a better control of comorbidities. Duodenal switch (DS) has proben to be the most …

  • 02 May, 2021
  • 1 location