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Found 13 clinical trials
Efficacy, Safety and Immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in Neonates

This phase III trial aims to assess the efficacy, safety and immunogenicity of Rotavirus RV3 Vaccine (Bio Farma) in neonates, lot-to-lot consistency, and antigen interference with co

Accepts healthy volunteers
  • 0 views
  • 27 Apr, 2022
  • 13 locations
A Trial to Assess the Safety, Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India

The trial will be a multinational, randomized, double-blind, double-dummy, endpoint driven, group-sequential, active comparator-controlled study, in which participating infants will be randomized 1:1 to receive either: 1) 90 g of the TV P2-VP8 vaccine IM plus oral placebo, or 2) Rotarix per os (PO) plus IM placebo. Participants will receive …

Accepts healthy volunteers
  • 0 views
  • 15 Feb, 2022
  • 1 location
Immunogenicity of H. Influenzae Type b PRP-OMP Vaccines in American Indian and Alaska Native Children (the HibVax Study)

The main goal of this study is to compare the Haemophilus influenzae type b antibody response in American Indian / Alaska Native (AI/AN) infants to two licensed vaccines: Vaxelis and PedvaxHIB.

Accepts healthy volunteers
  • 0 views
  • 18 Apr, 2022
Human Challenge With Live-attenuated Rotavirus to Assess Next-generation Rotavirus Vaccines in Africa

Despite the widespread introduction of vaccines against Rotavirus, Rotavirus continues to be a cause of significant morbidity and mortality in the developing world. This study will assess

  • 0 views
  • 28 Apr, 2021
  • 1 location
Response to Rotavirus Vaccine in Infants in Ho Chi Minh City in Vietnam

The primary objective is to measure the effect of host human genetics on the resulting immunological responses and long-term protection following rotavirus immunization of a study population of

rotavirus
rotarix
vaccination
rotavirus vaccine
Accepts healthy volunteers
  • 24 views
  • 03 Feb, 2022
  • 1 location
Efficacy and Safety of Two Doses of HIL-214 in Children

This is a randomized, placebo-controlled study that is being done to evaluate the safety and effectiveness of two doses of the HIL-214 vaccine compared to a placebo. The study will enroll 3000 children who will be 5 months of age at the time of the first dose study vaccine. The …

Accepts healthy volunteers
  • 0 views
  • 28 Jun, 2022
  • 7 locations
Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol)

The CDC and WHO have deemed the COVID-19 virus a global pandemic of unprecedented severity in modern times. In 2019, this novel Coronavirus (COVID-19) emerged from the Asian continent and has now caused upwards of 1million deaths and over 6 million infections globally. Currently, the estimated global economic impact is …

  • 543 views
  • 31 Mar, 2021
  • 1 location
Reducing Abundance of Human Papilloma Virus in Women by Taking Probiotic

The purpose of this study is to evaluate the efficacy of oral administration of probiotic at 9 log colony forming unit (CFU)/day to reduce vaginal abundance of HPV in women compared to placebo via the use of vaginal self-swab.

  • 0 views
  • 23 Apr, 2022
  • 1 location
Prevention of Irinotecan Induced Diarrhea by Probiotics

Diarrhea is a relatively common complication in patients with cancer. At its inception, several mechanisms participated; malabsorption on the basis of mucositis induced by chemotherapy, dysbiosis induced by broad-spectrum antibiotics and predisposition to infectious diarrhea in immunocompromised patients. Some cytostatics and their metabolites can also induce diarrhea directly due to …

cancer
irinotecan
primary cancer
antibiotics
lactic acid
  • 4 views
  • 27 Jan, 2022
  • 1 location
Canadian Rotavirus Surveillance Through the Immunization Monitoring Program Active (IMPACT)

Rotavirus Hospital Admissions Surveillance Retrospective surveillance for 2010 and 2011 for hospital admissions in children aged 0 to 16 years due to rotavirus

  • 202 views
  • 30 Jan, 2022
  • 12 locations