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Found 47 clinical trials
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Are you 65 or over with high cholesterol?

Are you 65 or over with high cholesterol?

  • 104 views
  • 08 Nov, 2020
  • 1 location
Effect of Rosuvastatin in Abdominal Sepsis

The purpose of this study is to determine whether rosuvastatin is effective as a coadjuvant drug in the integral management of abdominal sepsis acknowledged by surgery.

peritonitis
abdominal sepsis
cavity
  • 44 views
  • 07 Nov, 2020
  • 1 location
Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial Carcinoma

To explore the treatment efficacy of megestrol acetate plus rosuvastatin in patients with early endometrial carcinoma (EEC) seeking for conservative treatment.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Evaluation of the Effect of Rosuvastatin on Cisplatin-induced Nephrotoxicity and Ototoxicity

Cisplatin is an effective anti-cancer drug for the treatment of many solid tumors in humans. Although the clinical response to cisplatin chemotherapy is encouraging, the nephrotoxicity and ototoxicity of the drug makes it difficult to continue its administration in many cases. Cisplatin nephrotoxicity occurs through several mechanisms, mainly through the …

  • 0 views
  • 31 Mar, 2021
  • 1 location
Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial

This is a pragmatic randomized open-label study of the safety and efficacy of the combination of colchicine and Rosuvastatin in addition to standard of care (SOC) compared to SOC alone in

  • 0 views
  • 12 Mar, 2021
  • 4 locations
Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level

Early statin therapy in SLE patients that have high cholesterol level and other atherosclerosis risk should reduce atherosclerosis and coronary artery events in later course of disease. By the way, statin is used in restricted groups of rheumatologists due to awareness of side effects; myositis and hepatitis, that are frequently …

myositis
corticosteroids
autoimmune disease
  • 22 views
  • 07 Nov, 2020
  • 1 location
A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants

The purpose of this study is to evaluate the effect of macitentan at steady state on the pharmacokinetic (PK) of a single dose of riociguat and sildenafil (Part A); and rosuvastatin (Part B

  • 0 views
  • 28 Jan, 2021
  • 1 location
Statins for Venous Event Reduction in Patients With Venous Thromboembolism

along the walls of the vein control inflammation, which can prevent new blood clots from forming. The medication in this study, rosuvastatin, is approved in Canada for use as a cholesterol

  • 0 views
  • 05 Mar, 2021
  • 12 locations
RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)

-intensity statin to fulfill sufficient LDL-cholesterol lowering effect. We will evaluate whether additive ezetimibe with rosuvastatin will have comparable clinical efficacy in terms of clinical outcomes and

arteriopathy
hmg-coa reductase inhibitor
myocardial infarction
stroke
infarct
  • 13 views
  • 22 Jan, 2021
Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

pharmacokinetics (PK) of cytochrome P450 (CYP) enzyme probe substrates using a probe cocktail, on an organic anion-transporting polypeptide/breast cancer resistance protein (OATP/BCRP) substrate using rosuvastatin

  • 14 views
  • 16 Apr, 2021
  • 86 locations