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Found 349 clinical trials
French Adult Primary Immune Thrombocytopenia (FAITH)

Primary immune thrombocytopenia (ITP) is rare. First-line treatment is corticotherapy. Then, several second-line treatments (SLT) are available: splenectomy, off-label rituximab and

autoimmune thrombocytopenia
splenectomy
  • 3 views
  • 26 Feb, 2022
  • 1 location
Registry of the German CLL Study Group (CLL-Registry)

Long term follow-up of patients with chronic lymphocytic leukemia (CLL), B-prolymphocytic leukemia (B-PLL), T-cell prolymphocytic leukemia (T-PLL), Small lymphocytic lymphoma (SLL), T/Natural Killer large granular lymphocyte leukemia (T or NK-LGL), Hairy cell leukemia (HCL) and Richter's transformation

recurrent disease
richter syndrome
lymphoid leukemia
chronic lymphocytic leukemia
lymphoma
  • 23 views
  • 11 May, 2022
  • 1 location
A Study of Hairy Cell and Other Leukemias With a Focus on Recombinant Immunotoxins for Cancer Treatment

Background Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients and healthy volunteers. The investigators are particularly interested in samples from individuals who have diseases that can be treated with a new type of drug …

remission
hematocrit
Accepts healthy volunteers
cancer
platelet count
  • 8 views
  • 20 Oct, 2022
  • 1 location
Investigation of the B- and T-cell Repertoire and Immune Response in Patients With Acute and Resolved COVID-19 Infection

Background People who get infected with COVID-19 have an unpredictable risk to worsen and die. This makes it hard to decide who can quarantine at home and who should be treated at a hospital. Researchers think the risk may be related to how a person s B and T cells …

covid-19
Accepts healthy volunteers
  • 98 views
  • 29 Oct, 2022
  • 1 location
Clinical and Imaging Patterns of Neuroinflammation Diseases in China (CLUE)

CLUE is a prospective study to determine structural and functional changes of brain and spinal cord, as well as the inflammatory environment in patients with neuroinflammatory and demyelination disease. Subjects will receive new magnetic resonance (MR) technics including double inversion recovery (DIR) imaging diffusion kurtosis imaging (DKI), quantitative susceptibility mapping …

steroid therapy
myelopathies
demyelination
immunomodulation therapy
azathioprine
  • 0 views
  • 04 Oct, 2022
  • 1 location
Investigation on a Dynamic Cohort of Italian Patients With Active ITP (ITP0918)

The objective of the study is to produce a dynamic picture of the adult ITP natural history and management in Italy by collecting standardized information retrospective and prospective data of patients in active management through a nation-wide registry.

  • 0 views
  • 04 Oct, 2022
  • 26 locations
Spanish Registry of Systemic Treatments in Psoriasis (Biobadaderm)

The purpose of Biobadaderm is a to study the safety of systemic therapy in psoriasis.

systemic therapy
  • 45 views
  • 18 Apr, 2022
  • 13 locations
Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With BL/DLBCL

The trial SCCCG-BL/DLBCL-2017 is a collaborative prospective, multicenters, non-randomized, observational, cohort clinical study with participating centers of the South China Children's Cancer Group-Non-Hodgkin lymphoma group(SCCCG-NHL). The aim of the study is to evaluate efficacy and safety of stratified treatment based on risk factors of childhood and adolescents Burkitt lymphoma(BL)/diffuse large …

b-cell lymphoma
hodgkin's disease
burkitt's lymphoma
large b-cell lymphoma
cancer
  • 4 views
  • 26 May, 2022
  • 1 location
Ibrutinib Combined With Bendamustine and Rituximab in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged > 65 Years

This study is a prospective observational clinical trial. A total of 19 research centers were involved in this study. Each site plans to enroll 2-3 patients, and a total of 60 patients will be enrolled. Patients who met the diagnosis of mantle cell lymphoma by histological examination, ECOG (Eastern Oncology …

rituximab
bendamustine
chop regimen
measurable disease
r-chop
  • 0 views
  • 13 Jun, 2022
  • 1 location
Study of the Use of Venetoclax in Participants With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting

as a monotherapy or in combination with rituximab or obinutuzumab as prescribed at the discretion of the physician and in accordance with local clinical practice and label.

rituximab
TP53
chronic lymphocytic leukemia
lymphoid leukemia
venetoclax
  • 26 views
  • 04 Oct, 2022
  • 51 locations