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Found 45 clinical trials
Evaluation of The Efficacy of Triazavirin Versus Oseltamivir in Egyptian Patients Infected With COVID-19

The aim of this study is to evaluate the efficacy and safety (side effects and / or adverse effects) of Triazavirin and Oseltamivir as treatment of Coronavirus Disease 2019 in Egyptian patients in military hospitals.

  • 0 views
  • 28 Jul, 2021
  • 1 location
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.

The aim of the current clinical study is to evaluate the efficacy and safety of inhibition of Interleukin-1 receptor associated kinase 4 (IRAK4) in ameliorating the proinflammatory state and improving outcomes in severe COVID-19.

  • 0 views
  • 29 Jun, 2021
  • 1 location
COVID-19 Ring-based Prevention Trial With Lopinavir/Ritonavir

/ritonavir (LPV/r) is a promising candidate for both COVID-19 treatment and PEP, with a good safety profile and global availability. This is a cluster randomized controlled trial (RCT) of oral LPV/r as PEP

covid-19
lopinavir
lopinavir/ritonavir
ritonavir
  • 57 views
  • 24 Jan, 2021
  • 4 locations
Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19

Blinded, multicenter, placebo-controlled, randomized clinical trial evaluating lopinavir/ritonavir vs placebo in early outpatient treatment of adults with COVID-19

cough
fever
SARS
covid-19
respiratory tract infection
  • 94 views
  • 25 Jul, 2021
  • 6 locations
Randomised Evaluation of COVID-19 Therapy

RECOVERY is a randomised trial investigating whether treatment with Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Colchicine, IV Immunoglobulin (children only

lopinavir
covid-19
pneumonia
ritonavir
hydroxychloroquine
  • 0 views
  • 13 May, 2021
  • 3 locations
Dolutegravir and Darunavir Evaluation in Adults Failing Therapy

pharmaco-enhanced with ritonavir and dolutegravir and 2 prespecified NRTIs) with the WHO recommended regimen of 2NRTIs plus a ritonavir-boosted PI (Standard of Care (SOC)). 1,010 participants from 14

dolutegravir
ritonavir
HIV Vaccine
reverse transcriptase inhibitor
antiretroviral
  • 1172 views
  • 25 Mar, 2021
  • 32 locations
Appropriate Duration of Anti-Platelet and Thrombotic Strategy After 12 Months in Patients With Atrial Fibrillation Treated With Drug Eluting Stents

Atrial fibrillation patients with risk factors for stroke and systemic embolism require long-term anticoagulant therapy. Recently, non-vitamin K antagonist oral anticoagulant (NOAC) has shown their excellent safety and efficacy, and thus are widely accepted in clinical practice. Meanwhile, after percutaneous coronary intervention (PCI) using the drug-eluting stents due to coronary …

anticoagulants
fibrillation
infarct
noac
anticoagulation therapy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Prophylactic Anticoagulation for Catheter-related Thrombosis

The main objective of this study is to compare the efficacy and safety of aspirin, low molecule heparin and rivaroxaban for preventing catheter-related thrombosis in middle-to-high-risk ambulatory patients with cancer and implantable venous access ports.

  • 0 views
  • 25 Jan, 2021
  • 19 locations
Very Early Intensive Treatment of HIV-Infected Infants to Achieve HIV Remission

The study will explore the effects of early intensive antiretroviral therapy (ART) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among HIV-infected infants.

lopinavir
HIV Vaccine
antiretroviral
nevirapine
antiretroviral therapy
  • 94 views
  • 26 Jul, 2021
  • 50 locations
Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

This is an open-label, single-sequence, multiple-dose, 3 cohort study to investigate the effects of DRV/RTV and/or ETR on the pharmacokinetics (PK) of GSK3640254 and the effects of GSK3640254 on the PK of DRV/RTV and/or ETR. This study will aid in understanding these interactions and resulting changes in exposure (if any) …

  • 0 views
  • 28 Jul, 2021
  • 1 location