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Found 61 clinical trials
A Trial of Lopinavir/Ritonavir Dosed According to the Who Pediatric Weight Band Dosing Guidelines

The main purpose of this study is to measure the amount of lopinavir/ritonavir (two anti-HIV medications) in the blood. Results from this study will be compared to the levels of the drugs

lopinavir/ritonavir
lopinavir
kaletra
HIV Vaccine
ritonavir
  • 340 views
  • 08 Nov, 2020
  • 56 locations
Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Two LNF-containing regimens will be evaluated in the D-LIVR Phase 3 study: (1) LNF/RTV/PEG IFN-alfa-2a and (2) LNF/RTV. Each of these arms will have efficacy endpoints that measure clinical benefit with regard to viral suppression and alanine aminotransferase (ALT) normalization. For each LNF-containing regimen, a composite endpoint of EOT (48 …

  • 236 views
  • 17 Jan, 2021
  • 178 locations
Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

The purpose of this study is to see if emtricitabine is safe in children infected with HIV and to determine the best dose.

lopinavir/ritonavir
stavudine
emtricitabine
lamivudine
lopinavir
  • 151 views
  • 07 Nov, 2020
  • 2 locations
Efficacy of Favipiravir in Treatment of Mild & Moderate COVID-19 Infection in Nepal

COVID-19 has affected almost all countries in the world. Every other country is constantly working towards its treatment and development of vaccines, with little to no success so far. Recently, several regimens have been tried as antiviral medicine. Among these medicines, Favipiravir is considered a broad-spectrum antiviral with the spectrum …

  • 0 views
  • 10 Jan, 2021
  • 2 locations
A Study of Darunavir in Combination With Cobicistat or Ritonavir and Dabigatran Etexilate in Healthy Participants

The purpose of this study is to evaluate effect of single and repeated doses of darunavir (DRV) in combination with cobicistat (DRV/COBI) and with ritonavir (DRV+rtv) on the pharmacokinetics of

  • 5 views
  • 04 Nov, 2020
  • 1 location
Evaluate the Safety Tolerability and Antiviral Activity of GLS4 With Ritonavir in Patients With Chronic HBV Infection

The experiment is divided into two parts: Part 1 and Part 2.Part 1 was the initial treatment patient and Part 2 was the treated patient.

  • 4 views
  • 24 Jan, 2021
  • 37 locations
Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients

/Ritonavir for treatment of triple class failure in adult HIV-1 infected subjects. The purpose of this study is to look at the safety and efficacy of a combination of 3 new antiretroviral drugs

reverse transcriptase inhibitor
antiretroviral agents
oophorectomy
western blot
darunavir
  • 24 views
  • 08 Nov, 2020
  • 1 location
HIV Antiretroviral Drugs and Metabolism

Hypothesis 1: Ritonavir-based regimens increase triglycerides and VLDL by both increasing VLDL production and decreasing VLDL clearance. Specific Aim 1A: To quantify the effect of

lopinavir/ritonavir
atazanavir
antiretroviral agents
ritonavir
lopinavir
  • 6 views
  • 07 Nov, 2020
  • 1 location
Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Sofosbuvir in Treatment-na ve Patients With Chronic Hepatitis C Genotype 1

Multicenter, open-label, phase II safety and efficacy study of all-oral combination of narlaprevir/ritonavir and sofosbuvir in Treatment-nave Patients with Chronic Hepatitis C Genotype 1.

  • 0 views
  • 23 Jan, 2021
  • 5 locations
PI Vs. NNRTI Based Therapy for HIV Advanced Disease

Ritonavir boosted protease inhibitor based therapy will have equivalent antiviral efficacy over 48 weeks compared to NNRTI based therapy in patients who are antiretroviral therapy naïve

lopinavir/ritonavir
antiretroviral therapy
antiretroviral agents
lamivudine
protease
  • 32 views
  • 07 Nov, 2020
  • 5 locations