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Found 3 clinical trials
Azacitidine Venetoclax and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

This phase I/II trial studies the best dose of venetoclax when given together with azacitidine and pevonedistat and to see how well it works in treating patients with newly diagnosed acute myeloid leukemia. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer …

myeloid neoplasm
hydroxyurea
myeloproliferative disorder
FGFR1
periodic abstinence
  • 40 views
  • 18 Mar, 2021
  • 1 location
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

This phase Ib trial determines if samples from a patient's cancer can be tested to find combinations of drugs that provide clinical benefit for the kind of cancer the patient has. This study is also being done to understand why cancer drugs can stop working and how different cancers in …

sirolimus
doxorubicin
ruxolitinib
cabazitaxel
dasatinib
  • 0 views
  • 26 Jul, 2021
  • 1 location
Cancer in Inherited Bone Marrow Failure Syndromes

Congenital Neutropenia: neutropenia, pyogenic infections, bone marrow maturation arrest. Pearson's Syndrome: malabsorption, neutropenia, marrow failure, metabolic acidosis; ringed sideroblasts.

fanconi's syndrome
bone marrow failure disorders
thrombocytopenia
dyskeratosis congenita
pancytopenia
  • 43 views
  • 23 Sep, 2021
  • 1 location