Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 40 clinical trials
None
A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag

Oral selexipag is commercially available in several countries for the treatment of a particular group of pulmonary hypertension (PH) called pulmonary arterial hypertension (PAH). The aim of the present study is to investigate whether selexipag could be helpful to treat patients with another form of PH called sarcoidosis-associated pulmonary hypertension …

  • 0 views
  • 06 Oct, 2021
  • 77 locations
None
Prevalence of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism : (Preva-CTEPH)

The prevalence of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism (PE) varies widely (0.4% to 8.8%) in the literature. This large variation could be due to the inclusion of patients with pre-existing CTEPH revealed on the occasion of a recurrence of PE. However, the absence of hemodynamic data when …

diagnostic procedures
dyspnea
anticoagulants
acute pulmonary embolism
  • 38 views
  • 10 Oct, 2021
  • 6 locations
None
Regression of Fibrosis & Reversal of Diastolic Dysfunction in HFPEF Patients Treated With Allogeneic CDCs

status (QOL scores), exercise tolerance (6MHW), exercise hemodynamics (supine exercise ergometry during right heart catheterization), myocardial interstitial fibrosis (MRI with native T1 mapping and

diuretics
heart disease
right heart catheterization
b-type natriuretic peptide
dyspnea
  • 54 views
  • 27 Mar, 2021
  • 1 location
None
Will Elevated Left Ventricle Filling Pressures Decrease by a Group Exercise Program in Patients With Hypertrophic CardioMyopathy?

randomized in a 1:1 ratio to 12 week of moderate-intensity exercise training or usual activity level. Assessments will include right heart catheterization, echocardiography, cardiopulmonary exercise testing

hereditary disease
cardiovascular disease
hypertrophy
dyspnea
exercise test
  • 7 views
  • 28 Jan, 2021
  • 1 location
None
Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires

have recommended right heart catheterization. Design Researchers will screen participants by reviewing their lab results and questionnaire answers.

right heart catheterization
heart surgery
  • 16 views
  • 24 Oct, 2021
  • 1 location
None
The Effect of TASH in Patients With HOCM

To examine patients with hypertrophic obstructive cardiomyopathy (HOCM) before and after septal alcohol ablation, to investigate the effect of the treatment in regards to changes in myocardial function, perfusion, invasive hemodynamics and exercise tolerance.

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Repurposing a Histamine Antagonist to Benefit Patients With Pulmonary Hypertension

This is a Phase 2, single-center, randomized placebo controlled trial of famotidine (an H2 receptor antagonist) in adults with pulmonary arterial hypertension. The study will evaluate the safety and clinical efficacy of a 24-week course of famotidine.

hypertension
right heart catheterization
pulmonary vasodilators
vasodilator
  • 52 views
  • 26 Jan, 2021
  • 1 location
None
Effect of Exercise and Respiratory Therapy on Right Ventricular Function in Severe Pulmonary Hypertension

Chronic pulmonary hypertension (PH) is associated with impaired exercise capacity, quality of life and right ventricular function.The disease is characterized by an increase of pulmonary vascular resistance and pulmonary arterial pressure, leading to right heart insufficiency. In later stages of the disease, the right heart is not able to further …

right heart catheterization
pulmonary arterial pressure
pulmonary arterial hypertension
heart failure
  • 7 views
  • 11 May, 2021
  • 1 location
None
Right Ventricular Pacing in Pulmonary Arterial Hypertension

In pulmonary arterial hypertension (PAH), progressive pulmonary vascular remodeling leads to supraphysiologic right ventricular (RV) afterload. Pharmacologic trials have shown that aggressive upfront treatment reversing pulmonary vascular remodeling successfully increases RV function and improves survival. To date, however, there are no proven treatments that target RV contractile function. Echocardiographic studies …

cardiac mri
heart disease
right heart catheterization
hypertrophy
hypertension
  • 0 views
  • 14 May, 2021
  • 1 location
None
Balloon Pulmonary Angioplasty in Non-operable CTEPH Patients

Balloon pulmonary angioplasty (BPA) emerged as a potential therapeutic option for non-operable patients with chronic thromboembolic pulmonary hypertension (CTEPH). The aim of this study was to evaluate the safety and efficacy of BPA in patients disqualified from surgery or suffered from persistent CTEPH despite pulmonary endarterectomy. This is a interventional …

endarterectomy
  • 1 views
  • 29 Aug, 2021
  • 1 location