Found 22 clinical trials
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Optimizing Antituberculosis Therapy in Adults With Tuberculous Meningitis
patients received antituberculosis treatment, which consisted of isoniazid (standard dose or high dose), rifampin, pyrazinamide, ethambutol for 3 months, followed by isoniazid, rifampin and ethambutol at
- 0 views
- 05 Feb, 2021
- 4 locations
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Phase 4 trial
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Accepting adults
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A New Treatment for Primary Smear-positive Pulmonary Tuberculosis With Interleukin-2
The purpose of the study is to compare the efficacy and safety of standard chemotherapy regimen 2HRZE/4HR plus IL-2 and standard regimen 2HRZE/4HR for newly diagnosed smear positive pulmonary tuberculosis.
- 0 views
- 28 Feb, 2021
- 16 locations
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Phase 2 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB
The overall goal of this exploratory proof-of-concept study is to determine whether, in participants with pulmonary tuberculosis caused by M. tuberculosis (MTB) with or without rifampin
- 16 views
- 24 Jan, 2021
- 1 location
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Phase 1 trial
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
A Study of Steady-state Rifampin on the Single-dose of Erdafitinib Tablets in Healthy Adult Participants
The main purpose of this study is to evaluate the effect of multiple doses of rifampin (a strong inducer of CYP3A4 and a moderate inducer of CYP2C9) on the pharmacokinetics of a single oral dose
- 0 views
- 27 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Neurology
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Currently Recruiting
A Pilot Study of Inflammatory Markers in Alzheimer's Disease
and rifampin. The results of this preliminary analysis will be used in defining the direction of further research.
- 163 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Assessing PA-824 for Tuberculosis (the APT Trial)
Assess the mycobactericidal activity of PA-824 (given at 200 mg daily) when added to first-line tuberculosis (TB) treatment (isoniazid, pyrazinamide, and a rifamycin antibiotic) over 12 weeks of treatment. Funding Source - FDA OOPD
- 198 views
- 25 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Enhanced Bioscaffold for Volumetric Muscle Loss
This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix AB Surgical Graft in the restoration of function in the setting of volumetric muscle loss after soft tissue trauma.
- 0 views
- 27 Jan, 2021
- 1 location
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Multi-country trial
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Phase 2 trial
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Accepting pediatric ages
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Accepting Seniors
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB.
Rationale Shorter regimens of high dose daily rifampin may be safe, and as effective as the standard rifampin regimen when taken for 4 months to treat latent TB
- 1 views
- 24 Jan, 2021
- 6 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Pediatrics/Neonatology
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Currently Recruiting
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in
- 513 views
- 18 Feb, 2021
- 30 locations
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Phase 2 trial
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Accepting pediatric ages
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Accepting Seniors
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1000s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Assessment of the Safety Tolerability and Effectiveness of Rifapentine Given Daily for LTBI
and rifampin (3HR), and 16 weeks of daily rifampin (4R). A total of 560 participants per arm (1,120 total) for the evaluation of safety and 1,700 participants per arm (3,400 total) for the evaluation
- 16 views
- 24 Jan, 2021
- 7 locations