Found 18 clinical trials
Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TB
This trial will assess the safety and efficacy of OPC-167832 combined with Delamanid and Bedaquiline in subjects with DS-TB administered for 4 months compared to rifampin, isoniazid, ethambutol
- 0 views
- 04 Oct, 2022
- 7 locations
Adjunctive Linezolid for the Treatment of Tuberculous Meningitis (ALTER)
This is a phase II randomized open-label trial of high versus standard dose rifampin (RIF) with or without linezolid (LZD) for the first 4 weeks of treatment for Tuberculosis Meningitis (TBM) at
- 0 views
- 04 Oct, 2022
- 1 location
Enhanced Bioscaffold for Volumetric Muscle Loss (MTEC VML)
This is a prospective, single center study conducted at the University of Pittsburgh designed to test the applicability and utility of XenMatrix™ AB Surgical Graft in the restoration of function in the setting of volumetric muscle loss after soft tissue trauma.
- 0 views
- 27 Feb, 2022
- 1 location
2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB. (2R2)
Rationale Shorter regimens of high dose daily rifampin may be safe, and as effective as the standard rifampin regimen when taken for 4 months to treat latent TB
- 1 views
- 13 Jun, 2022
- 8 locations
CSP #2001 - Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA Intrepid) (VA INTREPID)
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in
- 660 views
- 11 Oct, 2022
- 26 locations
Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI (ASTERoiD)
and rifampin (3HR), and 16 weeks of daily rifampin (4R). A total of 560 participants per arm (1,120 total) for the evaluation of safety and 1,700 participants per arm (3,400 total) for the evaluation
- 38 views
- 04 Oct, 2022
- 3 locations
Rapid Research in Diagnostics Development for TB Network (R2D2TB Network)
To reduce the burden of TB worldwide through more accurate, faster, simpler, and less expensive diagnosis of TB Every year, more than 3 million people with TB remain undiagnosed and 1 million die. Better diagnostics are essential to reducing the enormous burden of TB worldwide. The Rapid Research in Diagnostics …
- 10 views
- 28 Jun, 2022
- 11 locations
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)
This study evaluates the efficacy of rifampin in the treatment of hypercalcemia and/or hypercalciuria in participants with biallelic inactivating mutations of the CYP24A1 gene. Eligible subjects
- 57 views
- 10 Mar, 2022
- 1 location
Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex Disease (MAC2v3)
evidence underlying the current treatment recommendations has come from observational studies in which either a macrolide has been combined with rifampin and ethambutol, or in some cases combined with
- 380 views
- 04 Oct, 2022
- 22 locations
Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)
also takes metformin. Participants will have a chance to be put on either: 1) standard TB medicines (isoniazid, rifampicin, ethambutol and pyrazinamide for two months, continuing isoniazid and rifampin
- 0 views
- 01 Jul, 2022
- 1 location
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