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Found 183 clinical trials
Ketoconazole in Treating Participants With Ongoing EGFR Inhibitor-Induced Rash

This early phase I trial studies the side effects of ketoconazole and how well it works in treating participants with ongoing EGFR inhibitor-induced rash. Ketoconazole may reduce the symptoms related to EGFR inhibitor therapy and improve EGFR inhibitor-induced rash.

burning
skin biopsy
EGFR
egfr inhibitor
  • 10 views
  • 18 Apr, 2021
  • 4 locations
Rifaximin in Patients With Monoclonal Gammopathy

This trial studies how well rifaximin works in treating patients with monoclonal gammopathy. Antibiotics, such as rifaximin, may help to kill bacteria in the intestines and reduce the abnormal protein or cells in patients with monoclonal gammopathy.

multiple myeloma
antibiotics
  • 12 views
  • 26 Jan, 2021
  • 1 location
Effects of Curcumin Supplementation in Patients With Chronic Kidney Disease on Peritoneal Dialysis

The objective of this study is to assess whether supplementation with curcumin could modulate the intestinal microbiota, reducing levels of inflammatory markers of oxidative stress, uremic toxins and inflammasome, in patients with chronic kidney disease in peritoneal dialysis.

  • 0 views
  • 26 Jan, 2021
  • 1 location
Alpelisib in Treating Participants With Transorally Resectable HPV-Associated Stage I-IVA Oropharyngeal Cancer

This phase II trial studies how well alpelisib works in treating participants with human papillomavirus(HPV)-associated stage I-IVA head and neck cancer that can be removed by surgery. Alpelisib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Nelfinavir Cisplatin and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery

This phase I trial studies the side effects and best dose of nelfinavir when given together with cisplatin and external beam radiation therapy in treating patients with vulvar cancer that has spread to nearby tissue or lymph nodes (locally advanced) and cannot be removed by surgery. Nelfinavir is an antiviral …

  • 0 views
  • 25 Jan, 2021
Ellagic Acid Urolithin and Colonic Microbial Communities Affected by Walnut Consumption

Briefly, this is a 28-day dietary intervention study participants will be asked to eat 2 ounces (52 grams) of walnuts every day for 3 weeks, and at the end of the study period they will come in for a colonoscopy. Participants will first start a 1-week run-in period where they …

  • 0 views
  • 25 Mar, 2021
  • 1 location
Microbiome in Cancer Patients With High Dose Chemotherapy With Stem Cell Transplantation

Numerous in vitro and animal studies as well as growing number of clinical studies support the important role of microbiome in carcinogenesis and cancer treatment. Detection of changes in patients microbiome following hematopoietic cell transplantation/CAR-T cell therapy and correlations with adverse transplant outcomes, mainly infectious complications, acute and chronic GvHD, …

  • 0 views
  • 13 Mar, 2021
  • 1 location
Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy

This phase II trial studies how well pembrolizumab works in treating patients with stage IV inflammatory breast cancer or triple-negative breast cancer that has spread to other places in the body (metastatic) or has come back (recurrent), and who have achieved clinical response or stable disease to prior chemotherapy. Immunotherapy …

breast carcinoma
pleural effusion
erythema
progesterone receptor
cancer
  • 32 views
  • 26 Jan, 2021
  • 1 location
Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian Fallopian Tube or Primary Peritoneal Cancer

This pilot early phase I trial studies how adavosertib affects the tumor deoxyribonucleic acid (DNA) of patients undergoing surgery for high grade (fast growing or aggressive) ovarian, fallopian tube, or primary peritoneal cancer that has spread to other places in the body (advanced). Certain characteristics in the DNA of these …

cytoreductive surgery
cancer
neutrophil count
tubal ligation
absolute neutrophil count
  • 0 views
  • 25 Jan, 2021
  • 9 locations
Ixazomib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

This phase II trial studies how well ixazomib and rituximab work in treating patients with mantle cell lymphoma that has come back (relapsed) or does not respond (refractory) to BTK inhibitor treatment. Ixazomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. …

anthracyclines
cancer
rituximab
flow cytometry
neutrophil count
  • 1 views
  • 24 Jan, 2021
  • 1 location