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Found 185 clinical trials
A Study for the Identification of Biomarker Signatures for Diagnosis of Pulmonary Hypertension (PH) in Participants at Low or Intermediate Probability of PH Undergoing Cardiac Magnetic Resonance Imaging

biomarker (micro ribonucleic acid [RNA]); estimate the percentage of participants in the population considered clinically as not having PH that are positive for PH by cardiac magnetic resonance imaging (MRI

right heart catheterization
  • 0 views
  • 20 Jun, 2021
  • 5 locations
Immunological Biomarkers in Tuberculosis Management

mRNA (messenger Ribonucleic acid) expression of a panel of 150 genes; 3) a whole blood proteomic analysis; 4) an ex vivo immunophenotyping using flow and mass cytometry to characterize the lymphocyte

latent tuberculosis
interferon-gamma release assay
interferon
antibiotics
  • 0 views
  • 23 Jan, 2021
  • 1 location
Search for Predictive Factors of Resistance to Treatment for Metastatic Castration-resistant Prostate Cancer by Studying the Expression of microRNAs

won't benefit from the treatment chosen. It shows why resistant mechanisms to treatment need to be elucidated. MicroRNA (miR) are short RNA, implicated in messenger ribonucleic acid (mRNA) regulation

  • 0 views
  • 24 May, 2021
  • 1 location
Liquid Biopsies and IMAging for Improved Cancer Care

The recently developed liquid biopsy technology (to obtain and characterize tumour cells and tumour components like Deoxyribonucleic acid (DNA) or Ribonucleic Acid (RNA) from a simple blood draw

adenocarcinoma
renal function
measurable disease
  • 0 views
  • 27 Jun, 2021
  • 1 location
Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy

, showed that leflunomide was able to reduce the ability of the virus to make copies of itself. The coronavirus uses ribonucleic acid (RNA), a very long molecule that contains genetic information that is

  • 0 views
  • 14 May, 2021
  • 1 location
The Role of IL-22/IL-22BP Axis in Atopic Dermatitis

deserves further investigation. The main objective of this study is to better understand the potential protective role of IL-22BP through the assessment of its expression at the Messenger Ribonucleic Acid

  • 0 views
  • 27 Jan, 2021
  • 1 location
The BENeFiTS Trial in Beta Thalassemia Intermedia

ribonucleic acid (mRNA) to high levels in anemic nonhuman primates and in transgenic mice. The study drug acts by suppressing 4 repressors of the fetal globin gene promoter in progenitor cells from patients

thalassemia
  • 0 views
  • 02 Jun, 2021
  • 4 locations
Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features.

angiogenesis while MMP9 could promote vasculogenesis. The objectives are to correlate the plasma levels of MMP2 and MMP9 to their Ribonucleic acid (RNA) and protein tissue expression, activity and to

VEGFR2
MRI
growth factor
vascular endothelial growth factor
bevacizumab
  • 1 views
  • 22 Jan, 2021
  • 2 locations
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced Metastatic or Unresectable Cancer

This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's …

follicle stimulating hormone
nervous
solid tumor
lymphoma
monoclonal antibodies
  • 619 views
  • 04 Aug, 2021
  • 28 locations
Rifaximin in Patients With Monoclonal Gammopathy

This trial studies how well rifaximin works in treating patients with monoclonal gammopathy. Antibiotics, such as rifaximin, may help to kill bacteria in the intestines and reduce the abnormal protein or cells in patients with monoclonal gammopathy.

multiple myeloma
antibiotics
  • 13 views
  • 26 Jan, 2021
  • 1 location