Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 183 clinical trials
  • 4 views
  • 13 Jun, 2021
  • 67 locations
Doravirine/Islatravir (DOR/ISL) in Heavily Treatment-Experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)

/ISL to achieve 0.5 log10 decrease in HIV-1 ribonucleic acid (RNA) from study baseline (Day 1) to Day 8 is superior to placebo, each given in combination with failing antiretroviral therapy (ART).

  • 117 views
  • 10 Jun, 2021
  • 100 locations
OPTimizing Irradiation Through Molecular Assesment of Lymph Node After Primary Systemic Treatment

ribonucleic acid (mRNA) in the sentinel node. The result is expressed by the Tumour Load as number of copies per microliter. This technique has shown its diagnostic ability both without primary systemic

core needle biopsy
carcinoma
invasive breast cancer
female breast cancer
mastectomy
  • 0 views
  • 23 Jan, 2021
  • 22 locations
A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults

last participant completes their Week 48 study visit (Week 48 Secondary Endpoint study milestone). Thereafter, participants whose most recent HIV-1 ribonucleic acid (RNA) less than (<)50 copies

  • 0 views
  • 13 Apr, 2021
  • 44 locations
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

therapy, including incorporation of targeted agents and institution of genetic counseling and cancer surveillance. To evaluate and implement deoxyribonucleic acid (DNA) and ribonucleic acid (RNA

cyclophosphamide
lymphoid leukemia
idarubicin
daunorubicin
dasatinib
  • 230 views
  • 29 Jan, 2021
  • 7 locations
A Study of Rilematovir in Infants and Children and Subsequently in Neonates Hospitalized With Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus (RSV)

The purpose of the study is to evaluate the efficacy of rilematovir compared to placebo treatment with respect to the clinical outcome on the RSV Recovery Scale (RRS).

  • 0 views
  • 13 Jun, 2021
  • 206 locations
A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed

The purpose of this study is to evaluate the steady state pharmacokinetics (PK) of rilpivirine (RPV) and determine the appropriate dose of RPV in combination with other antiretrovirals (ARVs) in participants aged greater than or equal to 2 to less than 12 years and to evaluate the safety and tolerability …

rilpivirine
tenofovir
integrase inhibitors
raltegravir
dolutegravir
  • 53 views
  • 21 Apr, 2021
  • 19 locations
PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy)

Open-label, multicenter, dose titration and four-arm expansion trial to evaluate the safety, tolerability, immunogenicity, and preliminary efficacy of W_pro1 cancer vaccine (W_pro1) monotherapy or in combination with cemiplimab in patients with metastatic castration resistant prostate cancer (mCRPC: Part 1 and Part 2 Arms 1A and 1B) and in patients with …

cancer vaccine
prostatectomy
adenocarcinoma
luteinizing hormone
cabazitaxel
  • 57 views
  • 13 Jun, 2021
  • 28 locations
Whole Genome Trio Sequencing as a Standard Routine Test in Patients With Rare Diseases - "GENOME FIRST APPROACH"

The GENOME FIRST APPROACH project will enroll patients (n = 450) and their healthy parents with unclear molecular cause of the disease, suspected genetic cause of the disease and the healthy parents of those affected for trio analysis (N in total 1350).

  • 0 views
  • 27 Jan, 2021
  • 1 location
Platinum Based Chemotherapy or Capecitabine in Treating Patients With Residual Triple-Negative Basal-Like Breast Cancer Following Neoadjuvant Chemotherapy

This randomized phase III trial studies how well cisplatin or carboplatin (platinum based chemotherapy) works compared to capecitabine in treating patients with remaining (residual) basal-like triple-negative breast cancer following chemotherapy after surgery (neoadjuvant). Drugs used in chemotherapy, such as cisplatin, carboplatin and capecitabine, work in different ways to stop the …

oophorectomy
carcinoma in situ
neuropathy
axillary lymph node dissection
sentinel lymph node biopsy
  • 508 views
  • 24 Jan, 2021
  • 703 locations