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Found 187 clinical trials
A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

The purpose of the study is to evaluate on-treatment efficacy against hepatitis D virus (HDV) of JNJ-73763989 + nucleos(t)ide analog (NA) regimen compared to NA alone.

  • 0 views
  • 19 Jul, 2021
  • 71 locations
A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection

The purpose of this study is to evaluate the efficacy of 48-week study intervention with JNJ-73763989+JNJ-56136379+nucleos(t)ide analog (NA) regimen compared to NA alone assessed by HBsAg levels. This study is part of HepB Wings Platform Trial (PLATFORMPAHPB2001).

  • 6 views
  • 01 Mar, 2020
  • 32 locations
  • 0 views
  • 17 Jul, 2021
  • 58 locations
A Study of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants

The purpose of this study is to assess the antiviral activity of JNJ-64281802 versus placebo in terms of reduction of dengue virus 1 (DENV-1) ribonucleic acid (RNA) viral load (VL).

  • 45 views
  • 16 Jun, 2021
  • 1 location
Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients

To compare the sustained virological response (SVR = ribonucleic acid (RNA) - hepatitis C virus (HCV) undetectable at week 24 before end the treatment) in chronic hepatitis C patients

HIV Infection
peginterferon
ribavirin
ribonucleic acid
chronic hepatitis
  • 10 views
  • 07 Nov, 2020
  • 38 locations
Study of Biomarkers in Gynecological Cancers

has shown that changes in some genes and/or proteins may be important indicators for certain cancers and response to treatments. Genes are molecules made up of ribonucleic acid (RNA) and

cancer
cancer care
  • 2 views
  • 22 Apr, 2021
  • 1 location
  • 13 views
  • 02 Jul, 2021
  • 14 locations
Effects of Bronchial Segmental Endotoxin Instillation in Humans

, called microRNA (or micro ribonucleic acid). Objective To better how the body responds to infection. Also, to understand which cells in the lung

  • 0 views
  • 29 Jul, 2021
  • 1 location
Mocetinostat With Vinorelbine in Children Adolescents & Young Adults With Refractory and/or Recurrent Rhabdomyosarcoma

This phase I trial studies the side effects and best dose of mocetinostat when given together with vinorelbine to see how well it works in treating children, adolescents, and young adults with rhabdomyosarcoma that has spread to nearby tissues or lymph nodes and cannot be removed by surgery (locally advanced …

neutrophil count
vinorelbine
cancer
measurable disease
metastasis
  • 0 views
  • 19 Mar, 2021
  • 1 location
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia

"Methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia remains a major cause of community- or hospital-acquired bloodstream infections with an overall mortality estimated around 25%. Anti-staphylococcal penicillins (APs) such as oxacillin or cloxacillin are recommended as first-line agents. With the exception of first-generation cephalosporin (1GC) such as cefazolin, no alternative has yet proven …

  • 9 views
  • 25 Jan, 2021
  • 2 locations