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Found 62 clinical trials
Featured trial
ENLIGHTEN 1: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in adults

Evaluates the safety and efficacy of the LYR-210 matrix in patients with chronic rhinosinusitis without nasal polyps

nasal polyps
rhinosinusitis
  • 0 views
  • 07 Mar, 2022
  • 1 location
Featured trial
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate CBP-201 in Adult Patients with Chronic Rhinosinusitis with Nasal Polyps

To evaluate the efficacy of CBP-201 in patients with chronic rhinosinusitis with nasal polyps 

nasal polyps
rhinosinusitis
  • 0 views
  • 07 Mar, 2022
  • 1 location
Featured trial
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal

  • 0 views
  • 17 Feb, 2022
  • 1 location
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

fungal rhinosinusitis (AFRS) To assess the efficacy of dupilumab to reduce the need for rescue treatments To evaluate the efficacy of treatment with dupilumab in improving symptoms in

  • 8 views
  • 16 May, 2022
  • 36 locations
Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

fungal rhinosinusitis (AFRS) To assess the efficacy of dupilumab to reduce the need for rescue treatments To evaluate the efficacy of treatment with dupilumab in improving symptoms in

  • 9 views
  • 27 May, 2022
  • 38 locations
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal

  • 55 views
  • 14 May, 2022
  • 84 locations
The Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyps

This is an open-label, single-arm, multicenter, extension study to evaluate the long-term safety and efficacy of CM310 in patients with CRSwNP.

  • 0 views
  • 19 Dec, 2021
  • 1 location
Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52)

This is a Phase 4, open-label, single-arm, multicenter study to evaluate the efficacy and safety of dupilumab subcutaneous (SC) injection monotherapy in Japanese participants aged 18 or older with CRSwNP that is not adequately controlled with existing therapies. Duration of study period (per participant): Screening Period (2 to 4 weeks) …

  • 0 views
  • 13 May, 2022
  • 1 location
Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52)

This is a Phase 4, open-label, single-arm, multicenter study to evaluate the efficacy and safety of dupilumab subcutaneous (SC) injection monotherapy in Japanese participants aged 18 or older with CRSwNP that is not adequately controlled with existing therapies. Duration of study period (per participant): Screening Period (2 to 4 weeks) …

  • 0 views
  • 25 May, 2022
  • 1 location
Dupilumab for Prevention of Recurrence of CRSwNP After ESS

The investigators believe that administering Dupilumab during the pre- and peri-operative period of surgery for chronic rhinosinusitis with nasal polyps (CRSwNP) will safely downregulate Type 2

  • 0 views
  • 13 Jun, 2021
  • 1 location