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Found 535 clinical trials
A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy Subjects

This study was a randomized, double-blind, placebo-controlled phase I clinical trial of TQH3821 in adult healthy subjects, which plans to recruit 62 healthy subjects. The main purpose was to evaluate the safety and tolerance of TQH3821 in multiple doses, single and multiple times in healthy subjects and in combination with …

folic acid
Accepts healthy volunteers
methotrexate
folate
  • 0 views
  • 04 Jun, 2022
  • 1 location
Lysophosphatidic Acid / Autotaxin Axis in Rheumatoid Lung Disease

Rheumatoid arthritis (RA) is a common chronic systemic autoimmune relapsing disease characterized by joint inflammation. Beside arthritis leading to progressive joint damage and loss of function

interstitial lung disease
  • 4 views
  • 05 Aug, 2021
  • 1 location
MTX Hold During Covid-19 Booster

To investigate the effect of MTX discontinuation for 1 week on vaccination response to Covid-19 booster vaccination in RA patients.

methotrexate
  • 0 views
  • 25 Apr, 2022
  • 1 location
Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

Phase 2 study of the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of KPL-404 in subjects with moderate to severe Rheumatoid Arthritis.

rheumatoid factor
certolizumab pegol
golimumab
tocilizumab
antirheumatics
  • 0 views
  • 22 Apr, 2022
  • 9 locations
ATI-450 Plus MTX Versus Placebo Plus MTX in Patients With Moderate to Severe Active RA Who Have Had an Inadequate Response to MTX Alone

ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Patients with Moderate to Severe Active Rheumatoid Arthritis (RA) who have had an Inadequate Response to MTX Alone

  • 0 views
  • 16 Sep, 2022
  • 1 location
BARIcitinib Cognitive Emotional and Neural signaTuRE (BARICENTRE) (BARICENTRE)

Rheumatoid arthritis (RA) is a frequent and disabling disease, requiring early management to achieve clinical remission. Recently, baricitinib (jak1-jak2 inhibitor) has been shown to as an

  • 0 views
  • 20 Sep, 2022
  • 1 location
EFFECTS OF ABATACEPT on the Progression to Rheumatoid Arthritis(PALABA Study) (PALABA)

The main objective of this trial is to test the hypothesis that abatacept can reduce the progression of rheumatoid arthritis in ACPA+ or RF+ patients with palindromic rheumatism compared with

  • 0 views
  • 19 Apr, 2022
  • 1 location
The Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis Patients

Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by inflammation of the synovial joints and tendon sheaths. As a result of synovitis, progressive damage

  • 0 views
  • 18 Sep, 2022
  • 1 location
Safety and Efficacy of Low Temperature Rota-flush Solution in Patients With Severe Calcified Lesion (LOTA-II) (LOTA-II)

adherence is poor, which significantly increases the incidence of major adverse cardiovascular events (MACEs). Intracoronary rotational atherectomy (RA) was developed by David Auth in the early 1980s

troponin
single coronary artery
  • 0 views
  • 06 May, 2022
  • 9 locations
Avatrombopag in TPO-RA Refractory Aplastic Anemia Patients Safety and Efficacy Study --Single-arm, Multicenter, Open, Phase Π Clinical Study

combination with TPO-RA (including eltrombopta or hydtrombopta) for at least 3 months with no hematologic response at 6-month follow-up, and who were not suitable or unwilling to undergo hematopoietic stem

  • 0 views
  • 14 Sep, 2022
  • 1 location