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Found 535 clinical trials
Immune Response to SARS-CoV-2/COVID-19 Vaccination in Sarcoidosis

People with sarcoidosis, particularly those with significant lung and/or cardiac involvement, who become infected with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) are likely at increased risk of complications or death from COVID-19. While SARS-CoV-2 vaccines are highly efficacious in preventing COVID-19 in the general population, whether vaccination provides similar protection in …

Accepts healthy volunteers
  • 14 Dec, 2021
  • 1 location
Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS Study

The Main Hypothesis of this extension trial is that among those who have successfully discontinued their DMT as part of the DISCOMS trial (i.e. did not have a new MS relapse or brain MRI lesion) and remain off DMT after DISCOMS are at no greater risk of new or worsened …

disease or disorder
brain mri
  • 22 Sep, 2022
  • 7 locations
Beyond Efficacy- Eliciting Preference for Face-to-face and Internet-based Psychotherapy Among People With Depression: Using Discrete Choice Experiment to Advance Future Service Implementation

The aim of this study is to strengthen the evidence base of clients' preferences of psychotherapy and to close the described literature gaps so as to inform public health resource reallocation and implementation of psychological services. The investigators aim to address the following research questions: Which psychological service attributes exert …

Accepts healthy volunteers
  • 18 Sep, 2022
  • 1 location
MIF Involvement in AML (MIFAML)

This study is an observational study of MIF involvement in retrospectively and prospectively included adult acute myeloid leukemia (AML). Standard care samples collected at diagnosis, after one course of treatment, at time of remission controls, and at time of relapse will be used. The first objective is to determine which …

adult acute myelogenous leukemia
  • 08 Jun, 2022
Medical Marijuana Use and Driving Performance: A Test of Psychomotor Function in Adults 50 and Older (ROAD ACE)

Objective of the Protocol: The primary aim of the current protocol is to examine whether or not habitual use of medical marijuana affects psychomotor functioning operationalized as driving performance. Secondary endpoints will examine whether type of medical marijuana used, frequency, dosage or route of administration is associated with adverse effects. …

chronic pain
medical marijuana
Accepts healthy volunteers
  • 17 Sep, 2022
  • 1 location