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Found 537 clinical trials
Validation of a New Scale of Balance Recovery Confidence for Community-dwelling Older Adults

Introduction: Patient-reported outcome measures (PROMs) provide clinicians with a greater understanding of patients' perceived ability in their physical performance. Existing PROMs on falls efficacy provide meaningful information about the perceived ability in older people to perform common activities of daily living without falling. However, the perceived ability to recover the …

Accepts healthy volunteers
  • 18 Nov, 2021
  • 1 location
Hydrocortisone Vs Prednisolone in AI (HYPER-AID) (HYPER-AID)

This study is designed to collect data on individuals with adrenal insufficiency who are changing treatments from hydrocortisone to prednisolone, or vice versa. It will compare anthropometric, biochemical and subjective health outcomes between both treatments.

replacement therapy
  • 05 Mar, 2022
  • 1 location
Atrial Late Gadolinium Enhancement in Patients With Repaired Congenital Heart Disease

In this research study the investigators want to learn more about how well the investigators can visualize scar tissue in the heart by MRI. In patients with congenital heart disease who need a procedure in the electrophysiology laboratory, how the MRI findings match the findings in the electrophysiology laboratory is …

  • 14 Oct, 2022
  • 1 location
Computed Tomography With Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability (CTMETS) (CTMETS)

The main aim of this study was to investigate which strategy can diagnose more accurately syndesmotic instability among an existing index test (ankle CT in neutral position) and two new add-on index tests (ankle CT in a stress position with extended-knees and ankle CT in a stress position with flexed-knees). …

ligament sprain
  • 27 Apr, 2022
  • 1 location
ILD-SARDs Registry and Biorepository

A complex interaction between demographic, environmental and genetic mechanisms impact the onset, severity and outcome of ILD-SARDs through dysregulation of the immune system and lung pro-biotic pathways. Comorbidity and genetic risk indicate that there are overlapping pathogenic mechanisms among SARDs, some of which underlie ILD in different SARDs. The purpose …

bronchoalveolar lavage
connective tissue disease
chest ct
lung disease
  • 18 Sep, 2021
  • 1 location

The aim of this study is to investigate the validity and reliability of BETY-BQ as a biopsychosocial assessment tool in individuals receiving radiotherapy.

  • 04 Oct, 2022
  • 2 locations
Biomarkers Predicting Acute Myocardial Infraction in Patients Without Standard Modifiable Risk Factors (BeyondSMuRFs)

Coronary heart disease (CHD) is the leading cause of mortality worldwide. Every year, millions of people suffer its most adverse manifestation, an acute myocardial infraction (AMI). The majority of these patients present at least one of the standard modifiable risk factors (SMuRFs). These include smoking, hypertension, dyslipidemia, and diabetes mellitus …

heart disease
myocardial infarction
  • 07 Oct, 2022
  • 1 location
Progression and Etiology of Cortical Porosity in Diabetic Bone Disease (PREPT2D)

Type 2 diabetes is associated with increased cortical bone porosity and increased fracture risk. The goal of this proposed study is to understand the longitudinal evolution of cortical bone porosity and to investigate the underlying biological processes that drive increased cortical porosity and fracture risk in the setting of diabetes. …

hemoglobin a1c
Accepts healthy volunteers
body mass index
  • 13 Jun, 2022
  • 1 location
Study to Evaluate Cerebral AneurysmFlow Results in Occlusion (CARO)

AneurysmFlow R1.0 is an approved (i.e. CE labeled, 510k, Health Canada), software tool intended to provide relevant information on the blood flow in a cerebral aneurysm and its parent artery based on angiography. It calculates the Mean Aneurysm Flow Amplitude (MAFA) ratio to measure the volumetric flow rate quotient before …

saccular aneurysm
cerebral aneurysm
  • 04 Oct, 2022
  • 4 locations
Nutrition as a Risk Factor and Predictor of the Outcome of Orthobiological Treatments for Knee Osteoarthritis (Nutririsk)

The general purpose of this study is to evaluate the relation between the nutritional status of patients, the features of the orthobiologics products used for patients' treatment and the clinical outcomes after one-step conservative regenerative treatment for knee osteoarthritis.

Accepts healthy volunteers
  • 18 Oct, 2022