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Found 535 clinical trials
  • 0 views
  • 22 Sep, 2022
  • 65 locations
A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

A randomized withdrawal study in which responders to open-label treatment with tofacitinib will be randomized in a 1:1 ratio to tofacitinib or placebo in a double-blind phase. In the double-blind phase "time to sJIA flare" will be evaluated as primary endpoint and subjects will be discontinued once they experience sJIA …

  • 134 views
  • 05 Jul, 2022
  • 39 locations
European Low and Intermediate Risk Neuroblastoma Protocol

long-term outcome; increase the amount of treatment (radiotherapy and 13-cis-RA (13-cis-Retinoic Acid) for poorly differentiated or undifferentiated histology INRG stage L2 NB or

  • 125 views
  • 23 Jan, 2021
  • 82 locations
COVID-19 VACCINE SAFETY AND EFFECTIVENESS

A longitudinal open-label study will include health professionals and patients with immune-mediated inflammatory diseases (IMID) who will receive the ChAdOx1 nCoV-19 vaccine (AZD1222), in a standard 3-dose schedule with an interval of 12 weeks (first-second dose) and 24 weeks (second-thrid dose), in the vaccination campaign against SARS-CoV-2 to assess the …

Accepts healthy volunteers
  • 0 views
  • 02 Dec, 2021
  • 1 location
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus (TN-22)

The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.

  • 694 views
  • 13 Feb, 2022
  • 51 locations
Splenic Stimulation for RA

(Period 3), and a Long-term Follow-up period (Period 4). Participants eligible for implant will have active rheumatoid arthritis (RA) and have an inadequate response or intolerance to at least two

DMARD
tumor necrosis factor
baricitinib
  • 8 views
  • 31 Oct, 2021
  • 4 locations
RhEumatoid Arthritis MEDIcation Adherence (REMEDIA)

Rheumatoid arthritis (RA) is a public health issue because of its frequency, its functional consequences, the risk of morbidity and mortality and the costs incurred. A collaborative

biologic disease-modifying antirheumatic drug
DMARD
methotrexate
antirheumatics
  • 0 views
  • 29 Jul, 2022
  • 1 location
Fibres Supplementation in Rheumatoid Arthritis (SUPER-FIBRES)

rheumatoid arthritis treated with only csDMARDs and a moderate disease activity will be recruited in each arm and 29 controls with mechanic disease (osteoarthritis, tendinitis). Collection: Blood

osteoarthritis
  • 0 views
  • 26 Mar, 2022
  • 1 location
A Pilot Proof of Concept Study of the Effects of Administration of SCFA in Rheumatoid Arthritis (EASi-RA)

onset rheumatoid arthritis (NORA) patients. Up to 50 participants will be included to obtain a sample size of at least 16 participants taking the oral supplement. The study team hypothesizes that oral

methotrexate
  • 0 views
  • 15 Dec, 2021
  • 1 location
Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis (RA-Diet)

The primary objective of this study is to assess if there is a significant difference in the mean disease activity score in individuals with RA participating in a dietary intervention compared

  • 0 views
  • 22 Jul, 2022
  • 1 location