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Found 13 clinical trials
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(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 148 views
  • 08 Nov, 2020
  • 1 location
ESTIMATION OF GINGIVAL CREVICULAR LEVEL OF YKL40

The presence of YKL- 40 an acute phase protein in both chronic periodontitis and rheumatoid arthritis. However, till date no studies has been done on the levels of gingival crevicular fluid YKL-40 following scaling and root planing, the present study which is first of its kind is designed to detect …

  • 7 views
  • 22 Jan, 2021
  • 1 location
ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy

Pulmonary Arterial Hypertension or PAH is a progressive condition for which there is no cure. Even with substantial pharmacologic advances in the modern treatment era, survival still remains unacceptably poor, as reported in large PAH registries. Preclinical studies suggest that the administration of allogeneic CDCs have the potential to reduce …

  • 97 views
  • 25 Mar, 2021
  • 1 location
STep-up and Step-down Therapeutic Strategies in Childhood ARthritiS

This study aims to compare the effectiveness of a conventional therapeutic regimen, based on treatment escalation (step-up strategy) and driven by the treat-to-target approach, with that of an early aggressive intervention based on the initial start of a combination of conventional and biological DMARDs (step-down strategy).

  • 0 views
  • 28 Mar, 2021
  • 1 location
Factors of ILD in Newly Diagnosed Rheumatoid Arthritis

(1) anti-CCP and rheumatoid factor measurement (good clinical practice) and a specific sample for the detection of the MUC5 promoter variant rs35705950. Our aim is thus to identify

cyclic citrullinated peptide antibody
rheumatoid factor
  • 1 views
  • 23 Jan, 2021
  • 1 location
Immune Profile of Saliva and Serum of Patients With Primary Sj gren s Syndrome

etiology, with the production of several autoantibodies such as antinuclear antibodies (ANA), anti-Ro/SS-A, anti-La/SS-B, rheumatoid factor (RF) and cryoglobulins. Recently, our group described a high

keratoconjunctivitis sicca
dry eyes
ss-b
rheumatoid factor
primary sjogren's syndrome
  • 149 views
  • 25 May, 2021
  • 3 locations
Azathioprine and Prednisone in the Treatment of Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a diffuse lung disease, associated with the histological appearance of usual interstitial pneumonia (UIP), with an inexorably deteriorating clinical course. Prognosis is poor, reported median survival is less than 3 years. The prevalence is estimated as being 3 to 10 per 100.000 in different Western …

pneumonia
prednisone
corticosteroids
ct scan
pulmonary disease
  • 31 views
  • 07 Nov, 2020
  • 1 location
Abatacept vs Tocilizumab for the Treatment of RA in TNF Alpha Inhibitor Inadequate Responders

Rheumatoid arthritis (RA) is the most common inflammatory rheumatoid disease in France, affecting 0.3% of the general population. Without effective treatment, the persistent inflammation causes invalidating pain and joint destruction, leading to major functional disability. Biological agents have been proposed for patients with RA who have the most severe form …

tocilizumab
tumor necrosis factor
DMARD
tumor necrosis factor inhibitors
roactemra
  • 7 views
  • 22 Jan, 2021
  • 1 location
Skeletal Muscle Dysfunction in Rheumatoid Arthritis (RA)

Muscle strength helps determine a person's quality of life and functional independence. Patients with rheumatoid arthritis often suffer from muscle weakness and a pre-diabetic condition called insulin resistance. By doing this study, the investigators hope to learn why patients with rheumatoid arthritis (RA) suffer from muscle weakness.

  • 36 views
  • 04 Mar, 2021
  • 2 locations
Prognostic Evaluation of Inflammatory Polyarthritis of Recent Onset

Inflammatory joint diseases are major causes of invalidity and morbidity. Rheumatoid arthritis (RA), the most frequent of chronic arthritides, affects close to 1% of the Canadian population. Direct and indirect costs of RA represent close to 1% of the gross national product. Recent evidence suggest that initiation of early (e.g., …

polyarthritis
rheumatoid arthritis
arthropathy
  • 8 views
  • 12 Mar, 2021
  • 1 location