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Found 163 clinical trials
EFFECTS OF ABATACEPT on the Progression to Rheumatoid Arthritis(PALABA Study) (PALABA)

The main objective of this trial is to test the hypothesis that abatacept can reduce the progression of rheumatoid arthritis in ACPA+ or RF+ patients with palindromic rheumatism compared with

  • 0 views
  • 19 Apr, 2022
  • 1 location
Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

Phase 2 study of the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of KPL-404 in subjects with moderate to severe Rheumatoid Arthritis.

hydroxychloroquine
certolizumab pegol
adalimumab
rituximab
tocilizumab
  • 0 views
  • 22 Apr, 2022
  • 9 locations
Interest of Continuous Non-Steroidal Anti-Inflammatory Drug Treatment in Ankylosing Spondylitis Patients Treated by Anti-TNF Therapy in the Prevention of Radiographic Outcomes (STOP)

Ankylosing spondylitis (AS) is a frequent chronic inflammatory rheumatic disease that affects the axial skeleton, starting in the sacroiliac joints and spreading to the spine in most patients

rheumatic diseases
NSAID
steroidal anti-inflammatory drugs
anti-tumor necrosis factor therapy
tumor necrosis factor
  • 236 views
  • 24 Mar, 2022
  • 16 locations
Impact of a Gluten-free Diet on Quality of Life in Patients With Axial Spondyloarthritis.

with inflammatory rheumatism who are on gluten-free diets (GFDs), despite the lack of reliable data from controlled studies. This study aims to determine the impact of a GFD on the quality of life of

NSAID
rheumatism
axial spondyloarthritis
DMARD
  • 0 views
  • 09 Jan, 2022
  • 1 location
Methotrexate in Patients With Early Rheumatoid Arthritis (MTXRA)

Rheumatology Quality Register (SRQ) is a nationwide quality register with the aim of continuously improving the treatment and follow-up of patients with rheumatic disease. Using this type of quality registers

corticosteroids
methotrexate
antirheumatics
  • 0 views
  • 04 Oct, 2022
  • 3 locations
Splenic Stimulation for RA

biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) or JAK inhibitors (JAKis). A sufficient number of participants will be enrolled so that approximately 28 participants will undergo device

tumor necrosis factor
baricitinib
DMARD
  • 8 views
  • 31 Oct, 2021
  • 4 locations
Physiotherapy of Axial Spondyloarthritis

investigators will first recruit up to 300 axSpA patients receiving care at the Royal National Hospital for Rheumatic Diseases (RNHRD) in Bath into a cohort and observe their standard of care outcomes. This

  • 0 views
  • 10 Oct, 2021
  • 2 locations
The Role of Tofacitinib in Steroid Withdrawal in Rheumatoid Arthritis

rheumatic drugs are ineffective in the treatment of RA. The addition of tofacitinib to patients may be beneficial to the treatment.

synovitis
stiffness
DMARD
tofacitinib
antirheumatics
  • 8 views
  • 22 Jun, 2021
  • 1 location
Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis (TOLERANT)

anti-rheumatic drugs (DMARD) will be included. Any combination and dose of DMARD is allowed, with exception of Janus kinase inhibitors. Concomitant use of a low dose of prednisone (7.5 mg per day or

DMARD
glucocorticoids
prednisone
remission
antirheumatics
  • 0 views
  • 10 Mar, 2022
  • 1 location
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis (CRI-RA)

As stated by the European League Against Rheumatism (EULAR) and the Société Française de Rhumatologie (SFR), treatment of patients with rheumatoid arthritis (RA) should target sustained

adalimumab
methotrexate
DMARD
tumor necrosis factor
tofacitinib
  • 0 views
  • 15 Mar, 2022
  • 6 locations