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Found 41 clinical trials
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD) (PROTECT-ICD)

revascularisation (PCI or CABG). ICD implantation after 40 days according to current guidelines (LVEF≤30%, or ≤35% with New York Heart Association (NYHA) class II/III symptoms) could be considered, if part of local

  • 267 views
  • 15 May, 2022
  • 26 locations
EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke - a prAgmatic, International, Multicentre, Randomized triaL (DISTAL) (DISTAL)

Acute ischemic stroke (AIS) is one of the main causes of disability and loss of quality adjusted life years. This study is to analyze whether endovascular therapy (EVT) in addition to best medical treatment (BMT) reduces the degree of disability and dependency in daily activities after a Medium Vessel Occlusion …

  • 0 views
  • 23 Oct, 2022
  • 18 locations
ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO (ISCHEMIA-CTO)

Study design Prospective randomized open labeled multicenter study Hypotheses In asymptomatic patients with ≥ 10% of myocardial ischemia: PCI (Percutaneous Coronary Intervention) with latest generation of drug eluting stents is superior to optimal medical therapy in terms of relative reduction in MACCE (Major Adverse Cardiovascular and Cerebrovascular events). In symptomatic …

percutaneous coronary intervention
infarct
myocardial infarction
medical therapy
ischemia
  • 56 views
  • 22 Mar, 2022
  • 15 locations
Total Arterial Revascularization (TAR)

Total arterial revascularisation with in-situ confihuration of BITA is superior than y-graft in patients underwent CABG.

revascularisation
bypass graft
arterial disease
stable angina
atherosclerosis
  • 14 views
  • 01 Feb, 2022
  • 1 location
Paclitaxel-coated Balloon for Treatment of De-novo Non-complex Coronary Artery Lesions

that at 12-month follow-up, DCB was non-inferior to DES (MACE [cardiac death, non-fatal myocardial infarction, and target-vessel revascularisation] rates: 8% vs. 9%). Although some small-scale

revascularisation
paclitaxel
percutaneous coronary intervention
infarct
myocardial infarction
  • 0 views
  • 30 Jun, 2021
  • 1 location
Very Early Versus Delayed Angiography +/- Intervention on Outcomes in Patients With NSTEMI (RapidNSTEMI)

Prospective, open, multicentre, randomised controlled trial in patients with higher risk non-ST elevation myocardial infarction acute coronary syndrome

  • 3 views
  • 26 Feb, 2022
  • 1 location
Cangrelor Versus Ticagrelor In Patients With Acute Myocardial Infarction Complicated With Initial Cardiogenic Shock (DAPT-SHOCK-AMI)

Multicenter randomized double blind trial comparing intravenous cangrelor and oral ticagrelor in patients with acute myocardial infarction complicated by initial cardiogenic shock and treated with primary angioplasty.

cold
percutaneous coronary intervention
infarct
myocardial infarction
vasopressor
  • 24 views
  • 24 Oct, 2022
  • 28 locations
The British Heart Foundation SENIOR-RITA Trial (SENIOR-RITA)

SENIOR-RITA is a multicentre prospective open-label trial randomizing patients presenting with type 1 NSTEMI aged ≥75 years between invasive and conservative treatment strategies, to compare time from randomisation to cardiovascular death or non-fatal MI

medical therapy
angiography
stemi
coronary revascularization
  • 311 views
  • 12 Apr, 2022
  • 31 locations
Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

This study aims to find out whether people with chronic kidney disease [CKD] should take low dose aspirin to reduce the risk of first heart attack or stroke (cardiovascular disease [CVD]). CKD is common and is associated with an increased risk of CVD. CVD is caused by small blood clots …

myocardial infarction
aspirin
glomerular filtration rate
stroke
primary prevention
  • 0 views
  • 25 Mar, 2022
  • 1 location
Pragmatic Randomised Trial of the ESC 0/1 Versus 0/3 Hour Troponin Pathway (MACROS2)

The primary objective of this study is to assess the feasibility and impact of implementing the ESC 0-1 hour high sensitive troponin pathway in clinical practice and with specific reference to the 0-3 hour pathway currently in use. The principal outcome measure will be the safety of the 0-1 hour …

troponin
chest pain
  • 0 views
  • 23 Apr, 2022
  • 1 location