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Found 426 clinical trials
Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes (IPAD)

Lowering of blood pressure (BP) in high-risk hypertensive individuals reduces major adverse cardiovascular and cerebrovascular events. Diabetic patients with hypertension benefit from BP lowering treatment. The present trial, IPAD in brief, is a randomized, open-label, parallel-designed, multicenter study involving nearly 12,000 patients to be recruited and to be followed up …

type 1 diabetes mellitus
hba1c
stroke
angiotensin
hemoglobin a1c
  • 28 views
  • 26 Mar, 2022
  • 1 location
Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen (TREOCAPA)

TREOCAPA is a Phase II/III European Multicentre study concerning the prophylactic treatment by Acetaminophen of extremely preterm infant during the first five days after birth. The Phase II is a dose finding phase in order to assess the minimum effective dose regimen of acetaminophen for the closure of PDA for …

  • 0 views
  • 26 Mar, 2022
  • 17 locations
30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants (HiLo)

Preterm birth, or birth before 37 weeks' gestation, is increasingly common, occurring in 8 percent of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29 weeks' gestation. At this gestational age, the lungs are not fully developed and it is not …

  • 0 views
  • 21 Jul, 2022
  • 3 locations
Patient Navigator Intervention for Diabetic Retinopathy (SEEN)

This is a pilot study of a patient navigator intervention for people living with diabetes and at high risk of diabetic blindness. The investigators are assessing the feasibility and acceptability of the intervention in preparation for a clinical trial.

eye exam
diabetes
blindness
  • 0 views
  • 29 Jul, 2022
  • 1 location
Phacoemulsification Combined With Intravitreal Injection of Ranibizumab Prevent Postoperative Capillary Non-perfusion Zone Progress in Non-proliferative Diabetic Retinopathy

Diabetic retinopathy has been found progress in 20-70% diabetic patient after cataract phacoemulsification surgery. Intravitreal injection of anti-VEGF Ranibizumab is an important treatment for

lucentis
background diabetic retinopathy
ranibizumab injection
vegf
proliferative diabetic retinopathy
  • 0 views
  • 09 Jun, 2022
  • 1 location
Oral Metformin for Treatment of ABCA4 Retinopathy

Background ABCA4 retinopathy is a genetic disease in which the ABCA4 protein is absent or faulty. It can cause waste material to collect in the eye and may cause

  • 8 views
  • 23 Jul, 2022
  • 1 location
Effect of OMEGA3 Supplementation in Diabetic Retinopathy

with minimal or moderate non proliferative diabetic retinopathy.

proliferative diabetic retinopathy
severe nonproliferative diabetic retinopathy
angiography
omega-3 fatty acid
background diabetic retinopathy
  • 0 views
  • 22 Aug, 2021
  • 1 location
Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG

To evaluate the differences in retinal function as measured by ERG in diabetics with and without retinopathy 2) the ability of the Chromatic Electroretinogram (chERG) to detect changes in global

severe nonproliferative diabetic retinopathy
proliferative diabetic retinopathy
angiography
flashing lights
background diabetic retinopathy
  • 71 views
  • 30 Apr, 2021
  • 2 locations
Diabetic Retinopathy Tethered Augmented Reality With Eye4 Study (DRTARES)

Diabetes has reached epidemic levels in North America and with it, diabetic retinopathy is increasingly affecting the vision of millions of people. Despite treatment many patients still have

visual loss
diabetes
  • 0 views
  • 08 Aug, 2022
  • 1 location
INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study (INSPIRE)

The central hypothesis is that inflammation mediators are biomarkers of both systemic diabetes and Diabetic Retinopathy (DR) progression in the aqueous and that sustained topical ketorolac

diabetes
antibiotics
vitrectomy
hemoglobin a1c
mediators
  • 0 views
  • 21 Mar, 2022
  • 1 location