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Found 449 clinical trials
A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (KALAHARI)

Part A of the study is conducted to select the THR-149 dose level. Part B of the study is conducted to assess the efficacy and safety of the selected dose level compared to aflibercept, up to Month 3. As from Month 3, in about half of the subjects, the effect …

diabetes
type 2 diabetes mellitus
edema
sd-oct
macular edema
  • 21 views
  • 27 Jul, 2022
  • 58 locations
Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies

The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which

Accepts healthy volunteers
mediators
  • 5 views
  • 23 Jul, 2022
  • 1 location
Multimodal Ophthalmic Imaging

, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea. The use of a high-speed acquisition imaging

  • 0 views
  • 23 Jan, 2021
  • 1 location
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care …

thyroid disease
glaucoma
diabetes
diabetic retinopathy
eye disorder
  • 697 views
  • 08 Sep, 2021
  • 2 locations
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits

Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course. It is essential to develop novel health care models, utilizing telemedicine, to improve the ability to detect glaucoma at an earlier stage, and to provide a platform …

diabetes
glaucoma
Accepts healthy volunteers
visual loss
eye disease
  • 0 views
  • 22 Apr, 2022
  • 1 location
Function Integrity of Neck Anatomy in Thyroid Surgery

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Village-Integrated Eye Worker Trial II - Pilot (VIEW II Pilot)

treatment. The leading causes of visual impairment are cataract and refractive error, followed by glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR). Loss of vision from these

age-related macular degeneration
glaucoma
Accepts healthy volunteers
visual impairment
eye disorder
  • 126 views
  • 04 Mar, 2022
  • 1 location
Manhattan Vision Screening and Follow-Up Study

The investigators are conducting a 5-year prospective, cluster-randomized controlled trial, funded by the Centers for Disease Control (CDC), which provides vision screenings to underserved, vulnerable New York City residents living in affordable housing buildings in Harlem and Washington Heights.

Accepts healthy volunteers
brimonidine tartrate ophthalmic solution
eye exam
  • 16 views
  • 27 Feb, 2022
Clinical Applications of Advanced Ophthalmic Imaging

The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased eyes and normal controls. There are two phases in this study. The first phase is an observational phase …

Accepts healthy volunteers
edema
macular edema
hemoglobin a1c
cognitive impairment
  • 630 views
  • 24 Jan, 2022
  • 1 location
NICU Antibiotics and Outcomes Trial (NANO)

morbidities in preterm infants that have previously been linked to EA, e.g. retinopathy of prematurity and bronchopulmonary dysplasia. Weight and length z-score, and head circumference, are standard measures

  • 36 views
  • 08 Aug, 2022
  • 13 locations