retinopathy Clinical Research Trials

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Found 502 clinical trials

Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.

participants are all adults aged 18 or over with first diagnosed rhegmatogenous total retinal detachment with retinal breaks located both in upper and lower retina. Also investigators include those patients

proliferative vitreoretinopathy

vitrectomy

cataract

light sensitivity

perfluorodecalin

9 views
08 Nov, 2020
1 location

Comparison of Two Techniques for Epiretinal or Internal Limiting Membrane Peel

Epiretinal membranes (ERM) are cellular membranes on the surface of the retina that result in distortion of the vision (metamorphopsia), and decreased best-corrected visual acuity. They

retinal vascular

vitrectomy

cataract

traction

retinal detachment

8 views
07 Nov, 2020
1 location

Measurement of Total Retinal Blood Flow and Oxygen Extraction in Patients With Diabetes and Healthy Subjects

, diabetic retinopathy and others relate to the damage of blood vessels. Given that the eye provides the unique possibility in the human body to directly visualize blood vessels, much interest has been

0 views
23 Jan, 2021

Intrapartum Maternal Oxygen Supplementation: Effects on the Mother and Neonate

is associated with adverse outcomes including retinopathy and abnormal neurodevelopment. Furthermore, excess O2 exposure is linked to free radical generation and subsequent oxidative cell damage

1 views
26 Apr, 2021
1 location

Treatment of Hereditary Hemorrhagic Telangiectasia of the Nasal Mucosa by Intranasal Bevacizumab : Search for Effective Dose

also used in ophthalmology intravitreal to reduce vascular proliferation in glaucoma retinopathy and certain corneal neovascularization. In 2009, Prithviraj reported the use of bevacizumab injection to

anti-angiogenic agents

arteriovenous malformation

bevacizumab

remissions

anemia

0 views
25 Jan, 2021
1 location

A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration

vascular diseases of the retina was not included in previous brolcuizumab studies. This single-arm, open-label, multicenter study is being performed to evaluate the efficacy and safety of

0 views
11 May, 2021
42 locations

Investigation of Therapeutic Efficacy and Safety of UMSCs for the Management of Retinitis Pigmentosa (RP)

Retinitis pigmentosa (RP) is the most common hereditary retinal disorder (accounts for 20% of children attending blind schools in Pakistan) which causes degeneration of rod and cone

0 views
01 Mar, 2021
1 location

Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment

hypotheses attribute a causal role to the circadian timing system. Bright white light exposure via the retina has been shown to reverse the symptoms of SAD. Recent physiological studies

thyroid function tests

recurrent major depressive episodes

structured clinical interview

phototherapy

depressive symptoms

262 views
07 Nov, 2020
1 location

A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU)

posterior segment, either primarily in the vitreous (intermediate uveitis), the choroid or retina (posterior uveitis), or involving the entire eye (panuveitis). The term "uveitis" denotes a heterogeneous

4 views
22 Apr, 2021
3 locations

Study of Intravitreal Microplasmin in Relieving Vitreo-Macular Adhesion in Neovascular Age-related Macular Degeneration

The purpose of this study is to determine whether microplasmin given by intravitreal injection is effective and safe for the treatment of wet age-related macular degeneration (AMD) in patients who have focal vitreomacular adhesion (VMA)

choroidal neovascular membrane

wet age-related macular degeneration

age-related macular degeneration

32 views
08 Nov, 2020
1 location

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Found 502 clinical trials