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Found 264 clinical trials
A 96-week, Two-arm, Randomized, Single-masked, Multi-center, Phase III Study Assessing the Efficacy and Safety of Brolucizumab 6 mg Compared to Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR

  • 13 views
  • 15 Oct, 2022
  • 73 locations
OTT166 in Diabetic Retinopathy (DR)

This study will evaluate the safety and efficacy of OTT166 Ophthalmic solution in participants with Diabetic Retinopathy.

diabetes
vegf
ophthalmic solution
severe nonproliferative diabetic retinopathy
edema
  • 0 views
  • 04 Oct, 2022
  • 7 locations
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2) (BabySTEPS2)

Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime. This study tests high

Accepts healthy volunteers
  • 0 views
  • 15 Mar, 2022
  • 1 location
Bevacizumab Treatment For Posterior Zone I Retinopathy of Prematurity (ROP4)

Type 1 retinopathy of prematurity in zone I represents the most severe type of ROP and has the worst prognosis. It is unknown whether low-dose bevacizumab will be successful in these severe

  • 8 views
  • 20 Oct, 2022
  • 22 locations
Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity (RoProp)

Extremely premature infants are at risk of developing a potentially blinding eye disease, called retinopathy of prematurity (ROP). Currently available treatment, consisting of laser surgery or

  • 0 views
  • 25 Oct, 2022
  • 1 location
Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients

A prospective, randomized, open-label, controlled clinical trial will be conducted at the endocrinology department - Ain Shams University (ASU) hospital. Sixty patients will be enrolled into the study. 30 of which will receive dapagliflozin 10mg tab once daily and the other thirty will receive their standard antidiabetic therapy for 12 …

hypoglycemic agents
diabetes
antidiabetic drugs
type 2 diabetes mellitus
oral hypoglycemic
  • 0 views
  • 05 Jul, 2022
  • 1 location
The Effect of Music on Pain, Comfort and Physiological Parameters During Prematurity Retinopathy Examination

It is planned to determine the effect of music during Retinopathy of Prematurity (ROP) examination on pain, comfort and physiological parameters in preterm infants. This is single-center

Accepts healthy volunteers
  • 0 views
  • 17 Jun, 2022
  • 1 location
A Randomized Trial of Low-Dose Bevacizumab Versus Laser for Type 1 Retinopathy of Prematurity (ROP3)

This randomized clinical trial will compare retinal outcomes with low-dose intravitreous bevacizumab (0.063 mg) versus laser photocoagulation as treatment for infants with type 1 retinopathy of

  • 0 views
  • 24 Oct, 2022
  • 19 locations
AI for the Detection of Retinal Disease and Glaucoma in Patients With Diabetes Mellitus in Primary Care

Background: Diabetic retinopathy (DR) is one of the most important causes of blindness worldwide, especially in developed countries. In diabetic patients, periodic examination of the back of the

blindness
glaucoma
diabetes
  • 10 views
  • 16 May, 2022
  • 1 location
Oral Hydroxychloroquine (HCQ) for Retinitis Pigmentosa Caused by P23H- Rhodopsin (RHO)

This research study is being done to learn what effect 12 months of treatment with oral hydroxychloroquine (HCQ) will have on the retina in people with retinitis pigmentosa (RP). The hypothesis

corrected visual acuity
retinal degeneration
retinopathy
genetic testing
antacids
  • 135 views
  • 21 Mar, 2022
  • 1 location