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Found 497 clinical trials
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Long-term effects of semaglutide on diabetic retinopathy in subjects with type 2 diabetes

We are seeking participants for a new clinical research study to evaluate the long term treatment effects of an investigational medication on diabetic retinopathy progression in adults with

hemoglobin a1c
diabetes
type 2 diabetes
type 2 diabetes mellitus
diabetes type 2
  • 72 views
  • 14 Jan, 2021
  • 1 location
Study to Assess the Efficacy Safety and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity

The primary objective of the study is to assess the efficacy of aflibercept compared to laser in patients diagnosed with retinopathy of prematurity (ROP). The secondary objectives of the study

  • 55 views
  • 30 May, 2021
  • 84 locations
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR

  • 0 views
  • 03 Aug, 2021
  • 82 locations
Effects of Closed-loop Automatic Control of FiO2 in Extremely Preterm Infants

prolonged hypoxemic episodes are associated with retinopathy of prematurity (ROP), impaired long-term development and death. Closed-loop automated control of the inspiratory fraction of oxygen (FiO2-C

  • 0 views
  • 22 Jan, 2021
  • 2 locations
Early CPAP in Respiratory Distress Syndrome

The purpose of this study is to establish if a strategy of EBCPAP application in a subgroup of VLBWI, 800 to 1500g birthweight, decreases the need for mechanical ventilation in this group, without affecting mortality.

intubation
continuous positive airway pressure
mechanical ventilation
  • 38 views
  • 07 Nov, 2020
  • 12 locations
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial

Non-infectious intermediate, posterior, and panuveitides are chronic, potentially-blinding diseases. Vision-threatening cases require long-term therapy with oral corticosteroids and immunosuppression. Based upon preliminary data, adalimumab, a fully-human, anti-TNFmonoclonal antibody, now US FDA-approved for uveitis treatment, may be a superior corticosteroid-sparing agent than conventional immunosuppressive drugs. The ADVISE Trial is multicenter randomized, …

mycophenolate
small molecule
tacrolimus
panuveitis
immunosuppressive agents
  • 103 views
  • 02 Aug, 2021
  • 33 locations
Intravitreal Bevacizumab for Retinal Disorders

Injection of bevacizumab (Avastin) for CNVM, Macular oedema due to diabetic retinopathy, vascular occlusion and other retinal disorders.

macular edema
vegf
retinopathy
bevacizumab
other retinal disorders
  • 23 views
  • 07 Nov, 2020
  • 1 location
Shiga Progression of Diabetes Nephropathy and Retinopathy

The purpose of this study is to investigate whether the oral anti-diabetic drug, Thiazolidine (TZD) is effective in suppression of onset or progressin of diabetic nephropathy in Japanese type 2 diabetic patients.

diabetic nephropathy
biguanide
hypertension
pioglitazone
  • 9 views
  • 07 Nov, 2020
  • 1 location
Intraoperative Analysis of the Central Retina in ERF

Changes in the retinal anatomy that occur in epiretinal fibrosis have not been sufficiently studied. It is possible that epiretinal fibrosis leads not only to traction dislocation of the macula, but also to ILM anatomical disorders.

  • 0 views
  • 27 Mar, 2021
  • 1 location
Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

Purpose:Retinopathy of prematurity (ROP) continues tobe a major cause of blindness in children. Although ablation of the retina with laser or cryotherapy reduces the incidence of

vegf
bevacizumab
antiangiogenic therapy
blindness
vascular endothelial growth factor
  • 4 views
  • 07 Nov, 2020
  • 1 location