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Found 18 clinical trials
Spontaneous Retinal Artery Pulses (SPARs) as a Prognostic Determinant of Central Retinal Vein Occlusions (CRVO) in Patients With or Without Intravitreal Aflibercept Injections

Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy. It induces circulatory slowdown and blood stasis, which can appear as retinal

  • 03 Nov, 2021
  • 3 locations
Retinal Microvascular Network and Coronary Revascularization Surgery at the Dijon University Hospital (MRCC)

extracorporeal circulation, the discriminative capacity of retinal vascular density to predict the occurrence of AKI within 7 days after surgery.

  • 28 Jun, 2022
  • 1 location
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2) (BabySTEPS2)

Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime. This study tests high-speed optical coherence tomography (OCT) technology compared to conventional color photographs at the bedside of very preterm infants in the …

Accepts healthy volunteers
  • 15 Mar, 2022
  • 1 location
Combination of Ranibizumab and Targeted Laser Photocoagulation (CoRaLaII)

Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the peripheral areas of capillary non-perfusion (up to 4 laser treatments within 1st year of the study). Based on the long-term observation after CoRaLa I study …

  • 24 May, 2022
  • 11 locations
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease

This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic

macular disease
proliferative diabetic retinopathy
macular degeneration
  • 04 Oct, 2022
  • 2 locations
Evaluating the Retinal Microvasculature in Mild Cognitive Impairment and Alzheimer's Disease Using Optical Coherence Tomography Angiography

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography angiography (OCTA) to assess the structure and function of the retinal microvasculature in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD) or other neurodegenerative disease, multiple sclerosis, and Huntington's disease.

mild cognitive impairment
huntington's disease
Accepts healthy volunteers
parkinson's disease
neurodegenerative disorders
  • 19 Oct, 2022
  • 1 location
Modifications in Retinal Microvascularization With Targeted Anti-angiogenic Therapy in Colorectal Cancer

antiangiogenic therapy are little described in the literature. The objective of this pilot study is to describe the evolution of the retinal vascular density of patients with antiangiogenic drugs. In addition

  • 20 Jul, 2021
  • 2 locations
Comparison of Posterior Ocular Changes Between Singleton Pregnancy and Multifetal Pregnancy.

>Increased corneal thickness and corneal curvature Increased lens thickness Increased retinal vascular density Increased choroidal thickness Decreased intraocular pressure -

  • 12 Sep, 2021
  • 1 location
Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease (COATS-VEGF)

Coats disease is a predominantly unilateral progressive retinal vascular disease, characterized by retinal telangiectasias with intra- or subretinal exudate deposits, which can lead to retinal

  • 12 Feb, 2022
  • 4 locations
The Efficacy and Safety of Adalimumab in Non-infectious Anterior Pediatric Uveitis With Peripheral Vascular Leakage

-infectious anterior uveitis with peripheral retinal vascular leakage on ultra wildfield fluorescence fundus angiography (UWFFA) will be included. They will be treated with a predesigned inflammatory control

non-infectious anterior uveitis
acute anterior uveitis
prednisolone acetate ophthalmic suspension
  • 17 Nov, 2021
  • 1 location