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Found 419 clinical trials
Featured trial
  • 20 views
  • 10 Mar, 2022
  • 1 location
A 96-week, Two-arm, Randomized, Single-masked, Multi-center, Phase III Study Assessing the Efficacy and Safety of Brolucizumab 6 mg Compared to Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy

The purpose of this study is to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR

  • 13 views
  • 15 Oct, 2022
  • 73 locations
Effects of Closed-loop Automatic Control of FiO2 in Extremely Preterm Infants

prolonged hypoxemic episodes are associated with retinopathy of prematurity (ROP), impaired long-term development and death. Closed-loop automated control of the inspiratory fraction of oxygen (FiO2-C

  • 0 views
  • 26 Sep, 2021
  • 10 locations
OTT166 in Diabetic Retinopathy (DR)

This study will evaluate the safety and efficacy of OTT166 Ophthalmic solution in participants with Diabetic Retinopathy.

macular edema
ophthalmic solution
vegf
diabetes
edema
  • 0 views
  • 04 Oct, 2022
  • 7 locations
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2) (BabySTEPS2)

Retinopathy of prematurity (ROP) is a disorder of development of the neural retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime. This study tests high

Accepts healthy volunteers
  • 0 views
  • 15 Mar, 2022
  • 1 location
Intraoperative Analysis of the Central Retina in ERF

Changes in the retinal anatomy that occur in epiretinal fibrosis have not been sufficiently studied. It is possible that epiretinal fibrosis leads not only to traction dislocation of the macula, but also to ILM anatomical disorders.

  • 0 views
  • 27 Mar, 2021
  • 1 location
Bevacizumab Treatment For Posterior Zone I Retinopathy of Prematurity (ROP4)

Type 1 retinopathy of prematurity in zone I represents the most severe type of ROP and has the worst prognosis. It is unknown whether low-dose bevacizumab will be successful in these severe

  • 8 views
  • 20 Oct, 2022
  • 22 locations
Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity (RoProp)

Extremely premature infants are at risk of developing a potentially blinding eye disease, called retinopathy of prematurity (ROP). Currently available treatment, consisting of laser surgery or

  • 0 views
  • 25 Oct, 2022
  • 1 location
Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening

instillation of the same mydriatic regimen, which constitutes routine care for pupil dilation during retinopathy of prematurity (ROP) screening in our neonatal intensive care unit. Comparison, also, will be

  • 0 views
  • 27 Oct, 2021
  • 1 location
Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients

A prospective, randomized, open-label, controlled clinical trial will be conducted at the endocrinology department - Ain Shams University (ASU) hospital. Sixty patients will be enrolled into the study. 30 of which will receive dapagliflozin 10mg tab once daily and the other thirty will receive their standard antidiabetic therapy for 12 …

antidiabetic drugs
oral hypoglycemic
hypoglycemic agents
diabetes
type 2 diabetes mellitus
  • 0 views
  • 05 Jul, 2022
  • 1 location