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Found 456 clinical trials
Safety Efficacy and Cost Analysis of the Conformable Thoracic Stent Graft With ACTIVE CONTROL

Study Design This is a prospective, multicenter, non-randomized clinical study in patients presenting thoracic aortic pathologies. Following a baseline assessment, the implantation procedure will be performed according to the Instructions for Use and local routine practice. A follow-up visit will be performed 30 days, 6, 12,24 and 36 months after …

  • 0 views
  • 29 Sep, 2021
  • 3 locations
Long Term Follow up of Children Enrolled in the REDvent Study

This is a prospective observational follow-up study of children enrolled in a single center randomized controlled trial (REDvent). Nearly 50% of adult Acute Respiratory Distress Syndrome (ARDS) survivors are left with significant abnormalities in pulmonary, physical, neurocognitive function and Health Related Quality of Life (HRQL) which may persist for years.Data …

lung injury
delirium
pneumonia
corticosteroids
mechanical ventilation
  • 15 views
  • 15 Feb, 2022
  • 1 location
ACE2 Gender Differences in Stroke With COVID-19

The new coronavirus SARS-CoV-2, causes the COVID-19 infection, which showed a form of neurovirulence involving the Central and peripheral Nervous Systems [Baig et al, 2020]. In a mouse model for human ACE2 expression, the virus entered the brain mainly through the olfactory bulb pathway [Netland et al, 2008], with an …

pneumonia
stroke
  • 0 views
  • 24 Nov, 2021
  • 1 location
Assessment of Microcirculation Alteration With Both Sublingual Microcirculation and Near-infrared Spectroscopy on ARDS

Microcirculatory alterations are frequently observed in critically ill and severe sepsis patients characterized by a decrease in capillary density and an increase in heterogeneity of perfusion. This derangements result in microcirculatory shunting and oxygen extraction deficit, and plays a major role in the pathophysiology of sepsis and multi-organ failure. Loss …

hypoxia
sepsis
assisted ventilation
mechanical ventilation
acute lung injury
  • 0 views
  • 21 Mar, 2022
  • 1 location
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study

In this study, the investigators hypothesize that studying monogenic variants with strong effect associated with severe insulin deficiency of Wolfram syndrome will provide important insights into the more complex type 1 and type 2 diabetes mellitus. Aim 1. Establish and maintain a registry of patients with Wolfram syndrome. An Internet …

deficiency
glucose intolerance
insulin
type 2 diabetes mellitus
ataxia
  • 232 views
  • 13 May, 2022
  • 1 location
COVID-19 Coagulopathy Extension Study

At the University of Iowa, the investigators led a multicenter randomized clinical trial comparing standard prophylactic dose to intermediate dose enoxaparin in hospitalized patients with COVID-19 (NCT04360824). As part of an exploratory biomarker component of this trial, blood samples were collected from hospitalized COVID-19 patients at enrollment and weekly for …

  • 0 views
  • 04 Oct, 2022
  • 1 location